Automatic Sampling

Reliably taking representative samples of oxygen or moisture-sensitive reactions and reactions at elevated pressure or sub-ambient temperatures is virtually impossible.  Highly toxic reactions present additional challenges.  The unique patented EasySampler probe enables the capture and immediate quenching of reactions to provide a sample representative of a reaction at the time of sampling.

EasySampler is immersed into a reaction, where it remains for the duration of the experiment. The sample pocket moves out and is filled with a sample. As the pocket withdraws, the sample is quenched immediately, at reaction conditions. The sample is then diluted to a user-specified concentration and ready for offline analysis.

Sampling reactions with precision is challenging.  Sampling is especially difficult for heterogeneous and multiphase reactions.  EasySampler samples from the same point in the reactor, into a pocket of fixed volume and includes solids.  Solids dissolution begins immediately, with the quench and dilution steps, delivering dissolved samples to gain representative, reproducible and accurate analytical data.

After quenching, the liquid handling system dilutes the sample to a user-specified concentration and transfers the sample to a vial, making it ready for offline analysis.  These steps can be used for derivatization, decreasing sample preparation time and eliminating human error.

Common EasySampler applications include:

Pfizer eliminated sampling challenges with an automated and robust inline method of taking representative samples from reactions, even under difficult conditions, for improved impurity profiling. 

Visit EasySampler eSupport for videos, manuals, application information and more.