Hydrogenation is one of the leading chemical reactions used because it allows the formation, in one single step, of C-C simple bonds from alkenes and alkynes, C-O bonds from ketones, aldehyde or esters and C-N (amines) from imines or nitriles.
Hydrogenation is influenced by several factors including type of catalyst, catalyst concentration, solvent, substrate purity, temperature and pressure. The optimization of a hydrogenation process requires selection of multiple parameters such as the correct catalyst, temperature, pressure, solvent, additives, and substrate-to-catalyst ratio.
By implementing hydrogenation technologies, scientists can achieve high productivity and volume efficiency, large reaction scope and high catalyst activity (low cost). Hydrogenation technologies have been developed to resolve key issues associated with the development, transfer and manufacturing of hydrogenation processes.
In situ FTIR analysis (ReactIR) provides continuous inline monitoring of hydrogenation processes in the lab, pilot plant and plant. Scientists use real time reaction information to determine reaction start and endpoints, reaction mechanisms and kinetics and chemical bond formation and breaking as well as tracking the formation of products and intermediates.
Synthesis workstations (EasyMax) provide precise control of temperature and other parameters to ensure highly reproducible experiments as well as developing robust processes at lab scale with knowledge about scalable parameters.