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Chemical Synthesis Reactors

Reproducible Chemistry.
Complete Experimental Insight.

METTLER TOLEDO automated synthesis reactors, including EasyMax, OptiMax, RC1, and RX-10, are intuitive platforms that accurately execute recipes and precisely control reaction parameters to ensure high reproducibility. These automated lab reactors support unattended, 24/7 operation with automatic data logging for immediate sharing and analysis. Well-established in the chemical and pharmaceutical industries, these automated reactors are essential for accelerating time-to-market while reducing R&D costs.

Contact us today to see how we can improve your synthesis workflows.
  • Integrated camera for continuous visual monitoring
  • Integrated pH monitoring and smart sensors
  • Automated stirring, dosing, sampling, and observation
  • Open interface and automation ready
  • Intuitive touchscreen and guided workflows
EasyMax 102i Hệ Thống Phản Ứng Tổng Hợp Hóa Học

EasyMax 102i

Standard and Advanced Models

Newly integrated real-time camera for complete experimental data capture.

Temperature Range: -40 °C – 180 °C
Operating Volume: 1 mL – 100 mL

EasyMax 402 Thermostat System

EasyMax 402

Basic and Advanced Models

Automated parallel reactor system with larger reaction vessels.

Temperature Range: -40 °C – 180 °C
Operating Volume: 40 mL – 400 mL

OptiMax 1001 Thermostat

OptiMax 1001

Pilot Scale Safety Applications

Simplify organic chemistry and eliminate dangerous handling of oil and ice baths.

Temperature Range: -40 °C – 180 °C
Operating Volume: 60 mL – 1,000 mL

ngón tay cái RX10

RX-10 Reactor Control System

Enhance Your Jacketed Lab Reactor

A touchscreen-based control unit to automate and monitor jacketed lab reactors.

Temperature Range and Operating Volume determined by the selected thermostat and JLR configuration.

RC1mx and HFCal

RC1mx HFCal™

Ensure Safety by Design

World-leading reaction calorimeter for process safety and scale-up.

Temperature Range: -70 °C – 300 °C
Operating Volume: 100 mL – 22 L

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What is a chemical synthesis reactor?

Chemical synthesis reactors are vessels in which chemical reactions take place. Reaction parameters, such as temperature, dosing, stirring, and sampling, are set to perform a synthesis reaction. The accuracy and precision of those reaction parameters play an important role in the selectivity, conversion, and reproducibility of the chemical reaction.

What are the types of chemical synthesis reactors?

There are three types of chemical reactors:

  1. Batch reactors
  2. Continuous stirred-tank reactors (CSTR)
  3. Plug flow reactors (PFR)

Batch reactors are stirred-tank reactors where the chemical reaction occurs in a confined space over a period of time.

Continuous stirred-tank reactors, or semi-batch reactors, add reactants continuously while removing by-products.

Plug-flow reactors are usually tubular reactors, where the conversion of chemical reactions is influenced by residence time.

What are the challenges with traditional synthesis reactors?

The preparation of manual lab equipment tends to be cumbersome and slow while putting the scientist at risk of exposure. Traditional setups also tend to be poorly controlled when limiting the range of reaction parameters, including T, p, pH, and sampling, which risks inconsistent and non-reproducible results. Information gaps limit understanding if data is not recorded or documentation is lost.

How can I automate my lab reactor?

chemical reactor control system

METTLER TOLEDO automated chemical synthesis reactor systems are designed for quick start-up, easy handling, precise control, intrinsic safety, and seamless data analysis and reporting.

  • Initiate recipes from the preconfigured home screen touchscreen or software.
  • Control reaction parameters from touchscreen or software, assuring better data quality and complete data sets.
  • Automate active cooling to allow fast temperature control and avoid unexpected side products. 
  • Automate data export to share visualization and traceability of results when you need them.

Additionally, the RX-10 reactor control system can connect to your existing jacketed lab reactor to automate cumbersome tasks for those who do not need full workstation setups. This reactor control system uses the same touchscreen interface as the full workstations for seamless workflows.

Do METTLER TOLEDO chemical synthesis reactors support Design of Experiment (DoE) studies?

doe design of experiments

doe design of experiments

Because our chemical synthesis reactors are designed to minimize bottlenecks and maximize the efficiency of the chemical laboratory, our models easily enable Design of Experiment (DoE) studies to produce high-quality experimental data. You can use METTLER TOLEDO reactors to optimize reaction and process parameters and explore how various combinations of settings such as temperature, pH, dosing, and stirring affect outcomes.

What is the difference between Basic/Standard and Advanced models?

EasyMax Advanced offers more features than its Basic/Standard counterpart. The Advanced personal synthesis workstation offers a more comprehensive platform for information management, including graph trends and task sequences on the touchscreen and full data capture/experiment documentation. You can also easily integrate and add the capabilities of:

  • iC Data Center™ software, to share data and build institutional knowledge
  • iControl™ software for planning, advanced control, and data evaluation
  • Heat flow calorimetry for process safety screening to identify, eliminate, and correct non-scalable reaction conditions

The 102 and 402 designations indicate the maximum volume and number of reactors available in the given workstation (i.e. 102 = up to two 100 mL vessels, while 402 = up to two 400 mL vessels)

See all Basic and Advanced models:

Can I connect my reactor to third-party accessories?

chemical synthesis reactor workstation

Yes! The Easy Control Box (ECB) accessory, purchased separately, extends your reactor for automated control and data capture of third-party devices, including sensors and dosing/sampling solutions.

ECB provides dosing control capabilities and easily connects commercially available pumps and balances for automated pre-programmed gravimetric or volumetric dosing. The accessory has plug-and-measure functionality with SmartConnect technology sensors. Control elements are automatically recognized, making reactor configuration simple and easy.  

Learn more about Easy Control Box (ECB).

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