Melting Point Certified Reference Standards

Certified Reference Standards

Melting Point Certified Reference Substances to Verify Instrument Accuracy

Certified melting point reference standards are substances that enable accurate temperature calibration and adjustment of melting point and dropping point instruments. Each high-purity METTLER TOLEDO reference substance comes with certified temperature values that are traceable to primary standards. Certified reference substances are provided in the range of 40 – 360 °C and are available as standard or as USP melting point reference standards.

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Advantages of Certified Reference Standards

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FAQs

Which melting point reference substances are included in the melting point accessory box?

The melting point accessory box contains the following melting point reference substances:

  • Benzophenone
  • Benzoic acid
  • Saccharin

Which melting point reference substances are included in the USP melting point accessory box?

The USP melting point accessory box contains the following melting point reference substances:

  • Caffeine
  • Vanillin
  • Acetanilide

Which melting point reference substances are included in the MP VPac™ ready-to-use performance verification kit?

The MP VPac™ contains the following melting point reference substances, each in 50 sealed standard METTLER TOLEDO melting point capillaries.

  • Phenyl salicylate
  • Benzoic acid
  • Saccharin

Which reference substances are suitable to be used for calibration and adjustment (performance verification) of a dropping point instrument?

METTLER TOLEDO reference substances such as benzophenone, vanillin, benzoic acid and potassium nitrate provide certified temperature values that can be used for temperature calibration of the DP70 and DP90 furnaces. Caffeine and saccharine cannot be used as they do not drop properly.

What are the United States Pharmacopeia (USP) requirements for USP reference substances?

USP specifies that the measured melting range must
a) Lie within the specified minimum and maximum temperatures (e.g. 81–83 °C for vanillin), and
b) Must not be broader than the specified admissible values (e.g. 1.5 °C for vanillin).
So, the permitted measured melting range for vanillin could be 81.0–82.5, 81.3–82.8 °C etc.