Particle Size Analyzers

A particle size analyzer is an analytical instrument that provides key insight to particle size, shape and count. This requires technology that measures, visualizes, and reports a particle size distribution for a given particle or droplet population. Particle size analyzers are important  during process development and quality control of particle systems to develop efficient processes and achieve high final product quality.

There are two types of particle size analyzers: inline and offline. In QC Labs, traditional offline particle size analyzers check the specification of particles at the end of a process to identify deviations from the required particle properties. In process development and R&D, inline particle analyzers are key to understanding changes in the particle system and the impact of critical process parameters. Inline particle analyzers like EasyViewer (with PVM technology) and ParticleTrack (with FBRM technology) continuously analyze particle systems as they exist in process.

Traditionally, sampling and offline particle size analyzer were used for product quality control. However, common sampling challenges, increasing pressure to expedite process development, and a higher demand for "right first time" processes required the development of an in situ particle size analyzer. The ability to measure particles as they naturally exist in a process has dramatically improved the ability to understand, optimize and control particle and droplet systems.

With ParticleTrack with FBRM technology and EasyViewer with PVM technology, METTLER TOLEDO is the world leader in real-time in situ particle size analyzers. The ability to measure particles as they naturally exist in a process has dramatically improved the ability to understand, optimize and control particle and droplet systems.

Common particle size analyzer applications include:

• Crystallization and Precipitation, Recrystallization, Polymorphism
• Particle and Droplet Processing
• Formulations and Product Development
• Flow Assurance in Oil & Gas Production

Since acquiring Lasentec in 2001, METTLER TOLEDO has continued to advance the development of FBRM and PVM particle size analyzers. With thousands of installations worldwide from the R&D laboratory to the manufacturing plant, our probe-based technologies are acknowledged as the gold standard for particle size distribution analysis.  Our technology, including crystallization equipment, measures and visualizes the rate and degrees of change in particle and droplet systems as they naturally exist in process.