Real Time Particle Size & Count Analysis

Particle Size & Count Analysis

As Particles Exist In-Process

Particle size & count analysis can be studies in real time with the probe-based ParticleTrack with FBRM technology. Obtain a real-time measurement of particle size, count, and shape:

• Direct in-process measurement with no sampling or by-pass loops required
• Study isolated regions (fine and coarse) of the particle population
• Study particles in opaque or translucent slurries and emulsions
• Directly observe how process changes impact particles
• Monitor particles from 0.5- 1000 μm at most process concentrations 

Inline Versus Offline Particle Size Distribution Analysis

Particle size analysis is often conducted offline under controlled conditions. This offline approach offers a reliable method to ensure the consistency and quality of particle-based products. However, offline particle size analysis can introduce time delays and sampling errors which make process optimization difficult. By studying particle size and count in-process, scientists can obtain information they need to improve processes quickly and with confidence. 

Focused Beam Reflectance Measurement (FBRM)

FBRM is the industry-standard measurement technique used for in-process measurement of particles. A highly precise chord length distribution (CLD), sensitive to particle size and count, is reported in real time without the need for sampling or sample preparation. No shape is assumed and the measurement can be applied at full process concentrations in opaque or translucent slurries and emulsions.

Study Particle Size and Count Over Time

Scientists insert ParticleTrack probes directly into process streams to monitor particle size and count continuously over time without having to take a sample. This unique information becomes the basis for effective understanding of every process that involves crystals, particles, and droplets.

Link the Process to the Particle System

With ParticleTrack with FBRM technology, scientists routinely determine how process parameters influence particle systems. The impact of process parameters on mechanisms such as growth, agglomeration, breakage, and shape change can be identified, allowing processes to be optimized and improved using evidence-based methods. 

Will ParticleTrack Work For My Application?

ParticleTrack with FBRM technology is used in many industries from research to manufacturing for in-process measurement.  Common application areas include:

• Crystallization and Precipitation
• Liquid Formulations
• Dissolution and Disintegration
• Flocculation
• Flow Assurance in Oil and Gas Production

Create Fit-for-Purpose Particle Systems

Scientists use ParticleTrack to determine how particles with the desired size and count can be delivered consistently. By choosing optimized process parameters during development, through scale-up and into production, scientists deliver high quality particle products to the market faster at a lower total cost and improved using evidence-based methods. 

Monitor and Correct Process Deviations

ParticleTrack with FBRM technology is used to monitor, troubleshoot and improve established processes in production. Difficult processes, where sampling is a challenge, can be monitored safely, ensuring particles with the highest possible quality are produced consistently. 

Monitoring Particle Mechanisms

ParticleTrack with FBRM technology is used to monitor particle system as they change over time. Mechanisms such as growth, agglomeration and breakage can be identified, quantified and related to the parameters chosen for the process.

Why is Particle Size Important?

Particles, crystals, and droplets occur in many chemical processes.  Particles, crystals, and droplets often pose challenges with optimizing product quality and process efficiency. Characterizing particle properties effectively, in particular particle size and count, allows processing problems to be solved and product quality to be improved.