Seminarium

Flow Chemistry as a Tool in Reaction Mechanism Elucidation

Exploring the Dynamics of Reactions

Mechanistic studies on chemical reactions are fundamental in the design of the optimal process. By truly understanding the processes we run, we can identify the strengths and limitations of the chemistry and perform targeted experimentation. However, depending on the complexity of the reaction, mechanistic studies can be lengthy and challenging to perform with high throughput. The aim of this talk is to demonstrate how flow chemistry can be used as a tool to accelerate mechanistic understanding through high quality data generation, automation, and adopting tools learnt through a successful collaboration with the University of Southampton.

About the Presenter

Dr. Tom Corrie

Principal Specialist Process Chemist, Syngenta

Tom completed his undergraduate degree at the University of Bristol before moving to the University of Edinburgh to complete his PhD under the supervision of Professor Guy Lloyd-Jones on the topic of gold-catalysed direct arylation. During this time, he gained an interest in the mechanisms of catalytic reactions, particularly on the application of kinetic simulations as a tool for probing selectivity and deactivation mechanisms in catalysis. He joined Syngenta as a process chemist in 2017 where he is now responsible for the kinetic modelling capability.