Bioburden and Total Organic Carbon (TOC) Analyzers - نظرة عامة - METTLER TOLEDO
Bioburden and Total Organic Carbon (TOC) Analyzers

Bioburden and Total Organic Carbon (TOC) Analyzers

Real-time microbial contamination and TOC analysis

 

Monitor organic contamination with on-line TOC analysis

Thornton total organic carbon sensors and analyzers provide fast, continuous measurement of ppb-level organic contamination. They utilize proven...

Thornton total organic carbon sensors and analyzers provide fast, continuous measurement of ppb-level organic contamination. They utilize proven UV oxidation and conductivity measurement technology to effectively determine TOC concentrations.

Our range of on-line TOC instruments

  • Meet pharmaceutical USP <643>, <645> and EP 2.2.44 requirements
  • Meet semiconductor ultrapure water monitoring requirements
  • Feature Intelligent Sensor Management diagnostics

 


 
7000RMS Microbial Detection Analyzer
On-line TOC Analyzer
Portable TOC Analyzers

7000RMS Microbial Detection Analyzer

On-line TOC Analyzers

Portable TOC Analyzers

Laser-induced fluorescence technology delivers instant detection and quantification of micro-organisms. Reduces lab measurements and increases process control.
On-line TOC analyzers provide continuous, fast and reliable monitoring of TOC levels, and help to ensure that TOC excursions will not be missed.
Proven, continuous measurement technology provides the fastest response time in a portable TOC analyzer. A valuable and convenient tool for water system diagnostics.
High sensitivity
Measurement of individual cells, reported as Auto Fluorescent Unit (AFU). Limit of detection is one AFU.
Easy to use
No sample preparation, staining or incubation required. Touchscreen operation.
Configurable to requirements
User-defined alarm and alert thresholds.
Real-time Microbial Detection
Results every two seconds.
Never miss an excursion with real-time measurement
Ensure compliance with global pharmacopeias
Monitor and record TOC levels for audit compliance
Versatile detection from ppm to sub-ppb levels
Easy-to-maintain with no moving parts or solutions
Reduce Sampling Time by 75%
Easy Data Capture and Analysis via USB
Compliant with Global Pharmacopeias
1500RV Rinse Verification System
TOC Pump Module

1500RV Rinse Verification System

TOC Pump Module

The 1500RV Rinse Verification System is a fully integrated solution for verification of Total Organic Carbon and conductivity of Clean-In-Place final rinse water.
Provides a highly stable, metered flow of process water to the TOC sensor to ensure reliable and consistent TOC measurement performance.
Reduce CIP Costs
by immediately verifying completion of your final rinse with real-time measurements for TOC and conductivity, and reduce water and energy usage during the rinse process
Maximize Production System Uptime
with on-the-spot results showing the success of your rinse process, and immediately restore the production system to operation with minimal risk
Quickly complete installation and startup
with a fully integrated, turn-key solution combining TOC and conductivity measurement without complex engineering
For applications where system pressure is too low to provide
adequate flow through the TOC sensor
For low-pressure applications where system pressure may vary routinely during operation
7000RMS Microbial Detection Analyzer

Laser-induced fluorescence technology delivers instant detection and quantification of micro-organisms. Reduces lab measurements and increases process control.

High sensitivity
Measurement of individual cells, reported as Auto Fluorescent Unit (AFU). Limit of detection is one AFU.
Easy to use
No sample preparation, staining or incubation required. Touchscreen operation.
Configurable to requirements
User-defined alarm and alert thresholds.
Real-time Microbial Detection
Results every two seconds.
On-line TOC Analyzer

On-line TOC analyzers provide continuous, fast and reliable monitoring of TOC levels, and help to ensure that TOC excursions will not be missed.

Never miss an excursion with real-time measurement
Ensure compliance with global pharmacopeias
Monitor and record TOC levels for audit compliance
Versatile detection from ppm to sub-ppb levels
Easy-to-maintain with no moving parts or solutions
Portable TOC Analyzers

Proven, continuous measurement technology provides the fastest response time in a portable TOC analyzer. A valuable and convenient tool for water system diagnostics.

Reduce Sampling Time by 75%
Easy Data Capture and Analysis via USB
Compliant with Global Pharmacopeias
1500RV Rinse Verification System

The 1500RV Rinse Verification System is a fully integrated solution for verification of Total Organic Carbon and conductivity of Clean-In-Place final rinse water.

Reduce CIP Costs
by immediately verifying completion of your final rinse with real-time measurements for TOC and conductivity, and reduce water and energy usage during the rinse process
Maximize Production System Uptime
with on-the-spot results showing the success of your rinse process, and immediately restore the production system to operation with minimal risk
Quickly complete installation and startup
with a fully integrated, turn-key solution combining TOC and conductivity measurement without complex engineering
TOC Pump Module

Provides a highly stable, metered flow of process water to the TOC sensor to ensure reliable and consistent TOC measurement performance.

For applications where system pressure is too low to provide
adequate flow through the TOC sensor
For low-pressure applications where system pressure may vary routinely during operation

المنشورات

Maximize Accuracy, Productivity and ROI

Process Analytics Product Catalog

الخدمات

Maximize Accuracy, Productivity and ROI

Documentation

المنشورات

Pure Water Analytics A Step Ahead for Pharmaceutical Compliance
Topics covered in this brochure are: Pharmaceutical Water conductivity and Total Organic Carbon Requirements, instruments that meet USP Purified Water...
Product Brochure: 6000TOCi with ISM
Continuous monitoring provides a real-time data advantage over batch or non-continuous methods of total organic carbon (TOC) measurement. Unlike at-li...
Process Analytics Service Brochure
Customer service at METTLER TOLEDO strives to provide our customers with added value whenever possible, including professional product service as well...
Semiconductor : Pure Water and Process Analytics for the Semiconductor Industry
Thornton instruments are specified in the majority of semiconductor manufacturing facilities worldwide to monitor and control ultrapure water systems....

دراسات الحالة

Turbidity Measurement Improves Beer Quality
In beer production, the quality of the wort influences the quality of the final product. For one of Brazil's major breweries, meeting international qu...
450TOC Portable Total Organic Carbon Analyzer
Global pharmacopeia regulations are driving TOC monitoring needs and taking up more technician time. The new portable 450TOC analyzer is a convenient...
In-line TOC Monitoring Reduces Production Downtime
An off-line TOC monitor missed critical diagnosis in a newly installed Water for Injection (WFI) storage tank. After installation of Thornton's on-lin...
Real-time TOC Analysis Safeguards Water Purity
To prevent bacterial growth, pharmaceutical-grade water systems require precise monitoring and control of TOC. A European producer of pure water syste...
Less Lab Testing and More System Uptime at French Medical Device Company
For a producer of medical biopolymers, quality from the purified water loop must be very high, and out-of-spec conditions responded to immediately. Sw...

التطبيقات

The impact of TOC in UPW systems for the Electronics Industry
Pure and Ultrapure water production requires the monitoring of organic contamination throughout the treatment process. The 5000TOC sensor provides con...
Problem of Organics in Power Plant Waters
While most efforts at producing pure water are aimed at removing minerals, these processes do not necessarily remove organic compounds. There is an in...
5000TOC Sensor - Total Organic Carbon Measurement in the Power Plant
This Application Note explains why total organic carbon (TOC) has been identified as an important measurement in power plant chemistry.

معلومات المنتج الموسَّعة

Total Organic Carbon (TOC) Frequently Asked Questions
Real-time system delivers instantaneous detection of microbial contamination. TOC instrumentation provides fast, continuous measurement of ppb-level o...
General Questions about Thornton Products
Thornton is the leader in pure and ultrapure industrial water monitoring instrumentation used in semiconductor, microelectronics, power generation, ph...

وثائق المنتج

Data Sheet: 6000TOCi with ISM
The 6000TOCi analyzer provides rapid, continuous measurement of TOC levels in your water system. Versus batch systems that measure at intervals, 6000T...
Operation Manual: 6000TOCi Sensor
The 6000TOCi sensor is a Total Organic Carbon sensor with ISM capabilities, designed to measure the concentration of organic substances in pure and ul...
5000TOCi Sensor Quick Start-Up Guide
This quick setup contains safety instructions, 5000TOCi sensor installation and start-up, electrical connection, menu structure, operation, general se...
Standard Operating Procedure - 450TOC Portable TOC Analyzer
This manual details standard operating procedure for TOC calibration, conductivity calibration, temperature calibration, flow rate calibration.
Operation Manual for 7000RMS Microbial Detection Analyzer
The METTLER TOLEDO Thornton 7000RMS (Real-time Microbial Detection System) is suitable for monitoring microbial contamination in high purity water sys...
Family Flyer: Continuous At-Line Microbial Monitoring For Pharmaceutical Waters
METTLER TOLEDO Thornton’s 7000RMS is an at-line analyzer for real-time measurement of microbial contamination (bioburden) in pharmaceutical water.

Manuals

Operation Manual for 4000TOCe Sensor
The 4000TOCe sensor is a Total Organic Carbon sensor designed to measure the concentration of organic substances in pure and ultra pure water applicat...
Standard Operating Procedure - 450TOC Portable TOC Analyzer
This manual details standard operating procedure for TOC calibration, conductivity calibration, temperature calibration, flow rate calibration.
 
 
 
 
 
 
 
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