Bioburden and Total Organic Carbon (TOC) Analyzers - نظرة عامة - METTLER TOLEDO
Bioburden and Total Organic Carbon (TOC) Analyzers

Bioburden and Total Organic Carbon (TOC) Analyzers

Real-time microbial contamination and TOC analysis

 

Monitor organic contamination with on-line TOC analysis

Thornton total organic carbon sensors and analyzers provide fast, continuous measurement of ppb-level organic contamination. They utilize proven...

Thornton total organic carbon sensors and analyzers provide fast, continuous measurement of ppb-level organic contamination. They utilize proven UV oxidation and conductivity measurement technology to effectively determine TOC concentrations.

Our range of on-line TOC instruments

  • Meet pharmaceutical USP <643>, <645> and EP 2.2.44 requirements
  • Meet semiconductor ultrapure water monitoring requirements
  • Feature Intelligent Sensor Management diagnostics

 


 
7000RMS Microbial Detection Analyzer
5000TOCi Total Organic Carbon Analyzer
450TOC Portable Total Organic Carbon Analyzer

7000RMS Microbial Detection Analyzer

5000TOCi Total Organic Carbon Analyzer

450TOC Portable Total Organic Carbon Analyzer

Laser-induced fluorescence technology delivers instant detection and quantification of micro-organisms. Reduces lab measurements and increases process control.
Provides continuous, fast and reliable monitoring of TOC levels in various applications. With continuous on-line measurements, the 5000TOCi sensor ensures TOC excursions will not be missed.
Employing proven continuous measurement technology, the 450TOC provides the fastest response available in a portable analyzer. Providing fast, convenient and affordable multi-point sampling capabiliti...
High sensitivity
Measurement of individual cells, reported as Auto Fluorescent Unit (AFU). Limit of detection is one AFU.
Easy to use
No sample preparation, staining or incubation required. Touchscreen operation.
Configurable to requirements
User-defined alarm and alert thresholds.
Real-time Microbial Detection
Results every two seconds.
Meets USP <643>, <645>, EP 2.2.44, ChP and JP16 requirements
for the pharmaceutical industry
Drastically reduces record keeping for release of water
through simplified data collection with innovative Peak and Average measurements
Improves the quality and reliability
of calibration and System Suitability Testing (SST)
Interfaces with the M800 multi-parameter analyzer/transmitter
Reduce sampling time by 75%
or more with on-the-spot results that eliminate lab analysis delays
Dual USB ports allow simultaneous USB printer operation
and data recording to a USB memory stick
Fully compliant with USP<643>, EP2.2.44, Ch P
and JP16 to meet pharmaceutical industry regulatory requirements
1500RV Rinse Verification System
4000TOCe Total Organic Carbon Sensor
TOC Pump Module

1500RV Rinse Verification System

4000TOCe Total Organic Carbon Sensor

TOC Pump Module

The 1500RV Rinse Verification System is a fully integrated solution for verification of Total Organic Carbon and conductivity of Clean-In-Place final rinse water.
Uses proven ultraviolet (UV) oxidation with differential conductivity to effectively determine TOC concentrations. Together with M300 single-channel transmitter offers a cost-effective solution.
Provides a highly stable, metered flow of process water to the TOC sensor to ensure reliable and consistent TOC measurement performance.
Reduce CIP Costs
by immediately verifying completion of your final rinse with real-time measurements for TOC and conductivity, and reduce water and energy usage during the rinse process
Maximize Production System Uptime
with on-the-spot results showing the success of your rinse process, and immediately restore the production system to operation with minimal risk
Quickly complete installation and startup
with a fully integrated, turn-key solution combining TOC and conductivity measurement without complex engineering
Provides a cost-effective solution for continuous TOC monitoring
to meet requirements of major pharmacopeias
Easy and economical integration into water purification make-up and distribution systems
Designed for simple interface with single-channel M300 transmitter
for process measurement in real time
For applications where system pressure is too low to provide
adequate flow through the TOC sensor
For low-pressure applications where system pressure may vary routinely during operation
7000RMS Microbial Detection Analyzer

Laser-induced fluorescence technology delivers instant detection and quantification of micro-organisms. Reduces lab measurements and increases process control.

High sensitivity
Measurement of individual cells, reported as Auto Fluorescent Unit (AFU). Limit of detection is one AFU.
Easy to use
No sample preparation, staining or incubation required. Touchscreen operation.
Configurable to requirements
User-defined alarm and alert thresholds.
Real-time Microbial Detection
Results every two seconds.
5000TOCi Total Organic Carbon Analyzer

Provides continuous, fast and reliable monitoring of TOC levels in various applications. With continuous on-line measurements, the 5000TOCi sensor ensures TOC excursions will not be missed.

Meets USP <643>, <645>, EP 2.2.44, ChP and JP16 requirements
for the pharmaceutical industry
Drastically reduces record keeping for release of water
through simplified data collection with innovative Peak and Average measurements
Improves the quality and reliability
of calibration and System Suitability Testing (SST)
Interfaces with the M800 multi-parameter analyzer/transmitter
450TOC Portable Total Organic Carbon Analyzer

Employing proven continuous measurement technology, the 450TOC provides the fastest response available in a portable analyzer. Providing fast, convenient and affordable multi-point sampling capabiliti...

Reduce sampling time by 75%
or more with on-the-spot results that eliminate lab analysis delays
Dual USB ports allow simultaneous USB printer operation
and data recording to a USB memory stick
Fully compliant with USP<643>, EP2.2.44, Ch P
and JP16 to meet pharmaceutical industry regulatory requirements
1500RV Rinse Verification System

The 1500RV Rinse Verification System is a fully integrated solution for verification of Total Organic Carbon and conductivity of Clean-In-Place final rinse water.

Reduce CIP Costs
by immediately verifying completion of your final rinse with real-time measurements for TOC and conductivity, and reduce water and energy usage during the rinse process
Maximize Production System Uptime
with on-the-spot results showing the success of your rinse process, and immediately restore the production system to operation with minimal risk
Quickly complete installation and startup
with a fully integrated, turn-key solution combining TOC and conductivity measurement without complex engineering
4000TOCe Total Organic Carbon Sensor

Uses proven ultraviolet (UV) oxidation with differential conductivity to effectively determine TOC concentrations. Together with M300 single-channel transmitter offers a cost-effective solution.

Provides a cost-effective solution for continuous TOC monitoring
to meet requirements of major pharmacopeias
Easy and economical integration into water purification make-up and distribution systems
Designed for simple interface with single-channel M300 transmitter
for process measurement in real time
TOC Pump Module

Provides a highly stable, metered flow of process water to the TOC sensor to ensure reliable and consistent TOC measurement performance.

For applications where system pressure is too low to provide
adequate flow through the TOC sensor
For low-pressure applications where system pressure may vary routinely during operation

المنشورات

Maximize Accuracy, Productivity and ROI

Process Analytics Product Catalog

الخدمات

Maximize Accuracy, Productivity and ROI

Documentation

المنشورات

Process Analytical Solutions - Optimizing Pharmaceutical Processes
Production processes and Purified Water quality can be assured through monitoring analytical parameters. For every stage of the manufacture of pharmac...
Family Flyer: Continuous At-Line Microbial Monitoring For Pharmaceutical Waters
METTLER TOLEDO Thornton’s 7000RMS is an at-line analyzer for real-time measurement of microbial contamination (bioburden) in pharmaceutical water.
MT Service brochure: A Partner You Can Trust to Get It Right from the Start
This brochure describes how METTLER TOLEDO support and service your measurement equipment through its entire life-cycle, from setup and configuration...
Pure Water Analytics A Step Ahead for Pharmaceutical Compliance
Topics covered in this brochure are: Pharmaceutical Water conductivity and Total Organic Carbon Requirements, instruments that meet USP Purified Water...

دراسات الحالة

Turbidity Measurement Improves Beer Quality
In beer production, the quality of the wort influences the quality of the final product. For one of Brazil's major breweries, meeting international qu...
In-line TOC Monitoring Reduces Production Downtime
An off-line TOC monitor missed critical diagnosis in a newly installed Water for Injection (WFI) storage tank. After installation of Thornton's on-lin...
450TOC Portable Total Organic Carbon Analyzer
Global pharmacopeia regulations are driving TOC monitoring needs and taking up more technician time. The new portable 450TOC analyzer is a convenient...
Less Lab Testing and More System Uptime at French Medical Device Company
For a producer of medical biopolymers, quality from the purified water loop must be very high, and out-of-spec conditions responded to immediately. Sw...

التطبيقات

5000TOC Sensor - Total Organic Carbon Measurement in the Power Plant
This Application Note explains why total organic carbon (TOC) has been identified as an important measurement in power plant chemistry.
The impact of TOC in UPW systems for the Electronics Industry
Pure and Ultrapure water production requires the monitoring of organic contamination throughout the treatment process. The 5000TOC sensor provides con...
Problem of Organics in Power Plant Waters
While most efforts at producing pure water are aimed at removing minerals, these processes do not necessarily remove organic compounds. There is an in...

معلومات المنتج الموسَّعة

Total Organic Carbon (TOC) Frequently Asked Questions
Real-time system delivers instantaneous detection of microbial contamination. TOC instrumentation provides fast, continuous measurement of ppb-level o...
General Questions about Thornton Products
Thornton is the leader in pure and ultrapure industrial water monitoring instrumentation used in semiconductor, microelectronics, power generation, ph...

وثائق المنتج

5000TOCi Sensor Quick Start-Up Guide
This quick setup contains safety instructions, 5000TOCi sensor installation and start-up, electrical connection, menu structure, operation, general se...
Standard Operating Procedure - 450TOC Portable TOC Analyzer
This manual details standard operating procedure for TOC calibration, conductivity calibration, temperature calibration, flow rate calibration.
Operation Manual for 7000RMS Microbial Detection Analyzer
The METTLER TOLEDO Thornton 7000RMS (Real-time Microbial Detection System) is suitable for monitoring microbial contamination in high purity water sys...
Family Flyer: Continuous At-Line Microbial Monitoring For Pharmaceutical Waters
METTLER TOLEDO Thornton’s 7000RMS is an at-line analyzer for real-time measurement of microbial contamination (bioburden) in pharmaceutical water.
Operation Manual for 4000TOCe Sensor
The 4000TOCe sensor is a Total Organic Carbon sensor designed to measure the concentration of organic substances in pure and ultra pure water applicat...
Data Sheet for 4000TOCe Sensor
Continuous on-line measurement total organic carbon monitoring, compact wall-mount sensor design/NEMA 4X enclosure for skid mounting.

Manuals

Standard Operating Procedure - 450TOC Portable TOC Analyzer
This manual details standard operating procedure for TOC calibration, conductivity calibration, temperature calibration, flow rate calibration.
5000TOCi Sensor Quick Start-Up Guide
This quick setup contains safety instructions, 5000TOCi sensor installation and start-up, electrical connection, menu structure, operation, general se...
 
 
 
 
 
 
 
Thank you for visiting www.mt.com. We have tried to optimize your experience while on the site, but we noticed that you are using an older version of a web browser. We would like to let you know that some features on the site may not be available or may not work as nicely as they would on a newer browser version. If you would like to take full advantage of the site, please update your web browser to help improve your experience while browsing www.mt.com.