Bioburden and Total Organic Carbon (TOC) Analyzers - نظرة عامة - METTLER TOLEDO

    Bioburden and Total Organic Carbon (TOC) Analyzers

    Real-time microbial contamination and TOC analysis

     

    Monitor organic contamination with on-line TOC analysis

    Thornton total organic carbon sensors and analyzers provide fast, continuous measurement of ppb-level organic contamination. They utilize proven UV oxidation and conductivity measurement technology to effectively determine TOC concentrations.

    Our range of on-line TOC instruments

    • Meet pharmaceutical USP <643>, <645> and EP 2.2.44 requirements
    • Meet semiconductor ultrapure water monitoring requirements
    • Feature Intelligent Sensor Management diagnostics

     

     
    7000RMS Microbial Detection Analyzer
    5000TOCi Total Organic Carbon Analyzer
    450TOC Portable Total Organic Carbon Analyzer

    7000RMS Microbial Detection Analyzer

    5000TOCi Total Organic Carbon Analyzer

    450TOC Portable Total Organic Carbon Analyzer

    Laser-induced fluorescence technology delivers instant detection and quantification of micro-organisms. Reduces lab measurements and increases process control.
    Provides continuous, fast and reliable monitoring of TOC levels in various applications. With continuous on-line measurements, the 5000TOCi sensor ensures TOC excursions will not be missed.
    Employing proven continuous measurement technology, the 450TOC provides the fastest response available in a portable analyzer. Providing fast, convenient and affordable multi-point sampling capabiliti...
    High sensitivity
    Measurement of individual cells, reported as Auto Fluorescent Unit (AFU). Limit of detection is one AFU.
    Easy to use
    No sample preparation, staining or incubation required. Touchscreen operation.
    Configurable to requirements
    User-defined alarm and alert thresholds.
    Real-time Microbial Detection
    Results every two seconds.
    Meets USP <643>, <645>, EP 2.2.44, ChP and JP16 requirements
    for the pharmaceutical industry
    Drastically reduces record keeping for release of water
    through simplified data collection with innovative Peak and Average measurements
    Improves the quality and reliability
    of calibration and System Suitability Testing (SST)
    Interfaces with the M800 multi-parameter analyzer/transmitter
    Reduce sampling time by 75%
    or more with on-the-spot results that eliminate lab analysis delays
    Dual USB ports allow simultaneous USB printer operation
    and data recording to a USB memory stick
    Fully compliant with USP<643>, EP2.2.44, Ch P
    and JP16 to meet pharmaceutical industry regulatory requirements
    1500RV Rinse Verification System
    4000TOC Total Organic Carbon Sensor
    TOC Pump Module

    1500RV Rinse Verification System

    4000TOC Total Organic Carbon Sensor

    TOC Pump Module

    The 1500RV Rinse Verification System is a fully integrated solution for verification of Total Organic Carbon and conductivity of Clean-In-Place final rinse water.
    Uses proven ultraviolet (UV) oxidation with differential conductivity to effectively determine TOC concentrations. Together with M300 single-channel transmitter offers a cost-effective solution.
    Provides a highly stable, metered flow of process water to the TOC sensor to ensure reliable and consistent TOC measurement performance.
    Reduce CIP Costs
    by immediately verifying completion of your final rinse with real-time measurements for TOC and conductivity, and reduce water and energy usage during the rinse process
    Maximize Production System Uptime
    with on-the-spot results showing the success of your rinse process, and immediately restore the production system to operation with minimal risk
    Quickly complete installation and startup
    with a fully integrated, turn-key solution combining TOC and conductivity measurement without complex engineering
    Provides a cost-effective solution for continuous TOC monitoring
    to meet requirements of major pharmacopeias
    Easy and economical integration into water purification make-up and distribution systems
    Designed for simple interface with single-channel M300 transmitter
    for process measurement in real time
    For applications where system pressure is too low to provide
    adequate flow through the TOC sensor
    For low-pressure applications where system pressure may vary routinely during operation
    7000RMS Microbial Detection Analyzer

    Laser-induced fluorescence technology delivers instant detection and quantification of micro-organisms. Reduces lab measurements and increases process control.

    High sensitivity
    Measurement of individual cells, reported as Auto Fluorescent Unit (AFU). Limit of detection is one AFU.
    Easy to use
    No sample preparation, staining or incubation required. Touchscreen operation.
    Configurable to requirements
    User-defined alarm and alert thresholds.
    Real-time Microbial Detection
    Results every two seconds.
    5000TOCi Total Organic Carbon Analyzer

    Provides continuous, fast and reliable monitoring of TOC levels in various applications. With continuous on-line measurements, the 5000TOCi sensor ensures TOC excursions will not be missed.

    Meets USP <643>, <645>, EP 2.2.44, ChP and JP16 requirements
    for the pharmaceutical industry
    Drastically reduces record keeping for release of water
    through simplified data collection with innovative Peak and Average measurements
    Improves the quality and reliability
    of calibration and System Suitability Testing (SST)
    Interfaces with the M800 multi-parameter analyzer/transmitter
    450TOC Portable Total Organic Carbon Analyzer

    Employing proven continuous measurement technology, the 450TOC provides the fastest response available in a portable analyzer. Providing fast, convenient and affordable multi-point sampling capabiliti...

    Reduce sampling time by 75%
    or more with on-the-spot results that eliminate lab analysis delays
    Dual USB ports allow simultaneous USB printer operation
    and data recording to a USB memory stick
    Fully compliant with USP<643>, EP2.2.44, Ch P
    and JP16 to meet pharmaceutical industry regulatory requirements
    1500RV Rinse Verification System

    The 1500RV Rinse Verification System is a fully integrated solution for verification of Total Organic Carbon and conductivity of Clean-In-Place final rinse water.

    Reduce CIP Costs
    by immediately verifying completion of your final rinse with real-time measurements for TOC and conductivity, and reduce water and energy usage during the rinse process
    Maximize Production System Uptime
    with on-the-spot results showing the success of your rinse process, and immediately restore the production system to operation with minimal risk
    Quickly complete installation and startup
    with a fully integrated, turn-key solution combining TOC and conductivity measurement without complex engineering
    4000TOC Total Organic Carbon Sensor

    Uses proven ultraviolet (UV) oxidation with differential conductivity to effectively determine TOC concentrations. Together with M300 single-channel transmitter offers a cost-effective solution.

    Provides a cost-effective solution for continuous TOC monitoring
    to meet requirements of major pharmacopeias
    Easy and economical integration into water purification make-up and distribution systems
    Designed for simple interface with single-channel M300 transmitter
    for process measurement in real time
    TOC Pump Module

    Provides a highly stable, metered flow of process water to the TOC sensor to ensure reliable and consistent TOC measurement performance.

    For applications where system pressure is too low to provide
    adequate flow through the TOC sensor
    For low-pressure applications where system pressure may vary routinely during operation

    المنشورات

    Maximize Accuracy, Productivity and ROI

    الخدمات

    Maximize Accuracy, Productivity and ROI

    Documentation

    المنشورات

    Process Analytical Solutions - Optimizing Pharmaceutical Processes
    Production processes and Purified Water quality can be assured through monitoring analytical parameters. For every stage of the manufacture of pharmac...
    Family Flyer: Continuous At-Line Microbial Monitoring For Pharmaceutical Waters
    METTLER TOLEDO Thornton’s 7000RMS is an at-line analyzer for real-time measurement of microbial contamination (bioburden) in pharmaceutical water.
    MT Service brochure: A Partner You Can Trust to Get It Right from the Start
    This brochure describes how METTLER TOLEDO support and service your measurement equipment through its entire life-cycle, from setup and configuration...
    Pure Water Analytics A Step Ahead for Pharmaceutical Compliance
    Topics covered in this brochure are: Pharmaceutical Water conductivity and Total Organic Carbon Requirements, instruments that meet USP Purified Water...

    دراسات الحالة

    Turbidity Measurement Improves Beer Quality
    In beer production, the quality of the wort influences the quality of the final product. For one of Brazil's major breweries, meeting international qu...
    In-line TOC Monitoring Reduces Production Downtime
    An off-line TOC monitor missed critical diagnosis in a newly installed Water for Injection (WFI) storage tank. After installation of Thornton's on-lin...
    450TOC Portable Total Organic Carbon Analyzer
    Global pharmacopeia regulations are driving TOC monitoring needs and taking up more technician time. The new portable 450TOC analyzer is a convenient...
    Less Lab Testing and More System Uptime at French Medical Device Company
    For a producer of medical biopolymers, quality from the purified water loop must be very high, and out-of-spec conditions responded to immediately. Sw...

    التطبيقات

    5000TOC Sensor - Total Organic Carbon Measurement in the Power Plant
    This Application Note explains why total organic carbon (TOC) has been identified as an important measurement in power plant chemistry.
    The impact of TOC in UPW systems for the Electronics Industry
    Pure and Ultrapure water production requires the monitoring of organic contamination throughout the treatment process. The 5000TOC sensor provides con...
    Problem of Organics in Power Plant Waters
    While most efforts at producing pure water are aimed at removing minerals, these processes do not necessarily remove organic compounds. There is an in...

    MSDS for TOC

    وثائق المنتج

    Operation Manual for 7000RMS Microbial Detection Analyzer
    The METTLER TOLEDO Thornton 7000RMS (Real-time Microbial Detection System) is suitable for monitoring microbial contamination in high purity water sys...
    Family Flyer: Continuous At-Line Microbial Monitoring For Pharmaceutical Waters
    METTLER TOLEDO Thornton’s 7000RMS is an at-line analyzer for real-time measurement of microbial contamination (bioburden) in pharmaceutical water.
    Operation Manual for 4000TOCe Sensor
    The 4000TOCe sensor is a Total Organic Carbon sensor designed to measure the concentration of organic substances in pure and ultra pure water applicat...
    Data Sheet for 4000TOCe Sensor
    Continuous on-line measurement total organic carbon monitoring, compact wall-mount sensor design/NEMA 4X enclosure for skid mounting.
    Product Flyer: 7000RMS Real-Time Microbial Detection
    Real-time Microbial Detection: Results every two seconds, no sample preparation or incubation required.
    Semiconductor : Pure Water and Process Analytics for the Semiconductor Industry
    Thornton instruments are specified in the majority of semiconductor manufacturing facilities worldwide to monitor and control ultrapure water systems....

    Manuals

    Operation Manual for 4000TOCe Sensor
    The 4000TOCe sensor is a Total Organic Carbon sensor designed to measure the concentration of organic substances in pure and ultra pure water applicat...
     
     
     
     
     
     
     
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