low retention pipette tips

Low Retention Pipette Tips

For Viscous and Low Surface Tension Liquids

A low retention pipette tip works well with viscous and low-surface-tension liquids. Viscous (e.g., glycerol) and low-surface-tension liquids (e.g., isopropyl alcohol) adhere to the inside of standard pipette tips, increasing experimental uncertainty. The unique Rainin molding process creates tips with a highly repellent coating – a “superhydrophobic” surface over the entire tip. This prevents any adhesion between samples and the polypropylene tip surface, facilitating enhanced fluid movement.

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Advantages of Low Retention Pipette Tips

low retention pipette tips

Advanced Repellent Surface

The super-repellent surface of Rainin LR tips "normalizes" the flow characteristics of fluids with diverse compositions and physical characteristics (viscosities, surface tension, density, hydrophobicity, etc.). The result: enhanced pipetting accuracy across a broader range of sample types. Rainin LR tips provide greater peace of mind and better data fidelity when pipetting.

Low Retention Pipette Tips

Ideal for Difficult Liquids

We employ a unique molding process to produce tips with a uniform field of highly-repellent fluoropolymer molecules that form an impenetrable “superhydrophobic” surface. The result: liquids and molecules are suspended above the polypropylene tip surface, allowing difficult liquids to glide effortlessly in and out of the tip.

Less Residual Volume

The uniform repellent fluoropolymer "field" on the surface of Rainin LR tips prevents any interaction between the sample and the polypropylene tip surface. In this short video, a propylene glycol-based food colorant demonstrates how Rainin LR low retention tips eliminate sheeting activity. By dramatically reducing the retained sample after dispensing, Rainin LR Tips eliminate a major source of pipetting inaccuracy.

Low Retention Pipette Tips

FinePoint Tips for Pipetting Accuracy

FinePoint tips taper to a fine orifice diameter. Their slender design, in combination with thin, flexible walls, creates an exceptionally supple tip that assists in sample touch-off. The narrow orifice aperture and thin wall surrounding the orifice provides minimal surface area for residual sample to adhere to during sample dispensing.

Low Retention Pipette Tips

Not All Low Retention Tips are Created Equal

More common manufacturing methods, such as dipping or tumbling tips in a fluoropolymer bath, can produce tips with incomplete and uneven coatings that can adversely affect pipetting accuracy. In addition, tips made with "diamond polished" molds – often touted as low retention – do nothing to prevent samples from reacting with the polypropylene and binding to the tip surface.


Rainin LR Low Rentention Tips Brochure
Learn how Rainin LR low retention tips improve pipetting accuracy by minimizing residual volume, particularly when transferring liquids such as viscou...
LTS LiteTouch System Product Brochure
By virtually eliminating friction, the Rainin LiteTouch System dramatically reduces the amount of force required to load and eject tips.
bioclean pipette tips datasheet
For successful experiments, pipette tips must be completely inert and not interfere with samples. Rainin BioClean tips are guaranteed to be free of RN...
Zero Contamination in Rainin Pipette Tips
A paper published in Science shows that by using certain polypropylene tips and tubes, experiments can be inhibited and results will be adversely affe...
sterile vs non sterile pipette tips
This white paper proves how there is essentially zero possibility for any Rainin pipette tip to contribute contaminants to customer samples.
Comparative Carbon Footprints Terrarack
METTLER TOLEDO Rainin is the pioneer of high purity ‘BioClean’ tips, creating a range of super-clean tips which are certified to be free of biological...
Counteracting Liquid Retention in Tips Benefits of Using Low Retention Tips
This white paper shows that Rainin LR tips are capable of “normalizing” the performance of liquids with diverse compositions and physical properties d...
How To Choose a Good Pipette Tip
Download an introduction and detailed advice on what to look for when choosing a good pipette tip, i.e., a tip that does not influence the experiment'...
How To Choose a Good Pipette Tip
Download an introduction and detailed advice on what to look for when choosing a good pipette tip, i.e., a tip that does not influence the experiment'...
Trace Organic and Inorganic Materials in pipette tips
To confirm that tips manufactured by Rainin do not provide sufficient quantities of contaminating inhibitors, a number of experiments were performed b...
Testing for Contaminants in Pipette Tips
To make sure that common reactions such as PCR and qPCR are not affected by these factors, Rainin regularly performs several tests on each lot of the...
Why Rainin Does Not Test for RNA
It may appear curious to some customers that Rainin tests its tips for human DNA contamination, but conducts no such tests for contaminating RNA.
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