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Case Study

Reduce Plate Counting by 25%

Case Study

Case Study on Real-time Microbial Monitoring

Remaining competitive in a global marketplace is a challenge for biotech and pharma companies, as they must focus on optimizing costs while improving efficiency and mitigating risk. This case study explains how a Chinese pharma company improved its water system process control.

They were taking 35-40 samples per water loop every day and aimed to reduce plate counting while maintaining product safety. The company implemented real-time microbial detection to reduce bioburden monitoring costs.

At the same time, this approach lead to a more comprehensive process control strategy. This case study provides more details about the Chinese pharmaceutical manufacturer. It explains how the costs of off-line microbial monitoring are continuously increasing and that a focus on plant efficiency through overall process control is vital. In the case study you can learn how rapid micro methods using the 7000RMS analyzer from METTLER TOLEDO were implemented.

The METTLER TOLEDO Thornton 7000RMS is an on-line water bioburden analyzer for real-time measurement of microbial contamination in pharmaceutical grade waters. This bioburden analyzer, when used in parallel with plate counting, offers a rapid microbial method (RMM) for better microbial control of your water system, reducing the risk of releasing contaminated water, increasing the speed of product release and improving process control.

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