Hydroformylation, or Oxo Synthesis, is used for the production of aldehydes from alkene compounds. The reaction is catalyzed by organorhodium or organocobalt compounds and adds a hydrogen atom to the C=C bond to form a C-C bond and a formyl group to the molecule, creating an aldehyde. Aldehyde compounds formed by hydroformylation are the basis for synthesis of many other compounds including alcohols, amines, carboxylic acids, etc. Thus, hydroformylation constitutes one of the most important chemical syntheses for producing bulk chemicals. Additionally, hydroformylation using catalysts with specific metal-ligand bonding is used in the chiral synthesis of more complex fine chemicals and pharmaceuticals. Though hydroformylation is considered a major homogeneous catalysis application, there are a number of heterogeneous hydroformylation systems that have been developed, often associated with rhodium complexes supported on various scaffolds.