Insight for Every Reaction Resources
Collection

Insight for Every Reaction

Collection

References and resources to help scientists solve complex chemistry problems.

Scientists must work with speed and accuracy to create commercially viable processes at multiple scales. Deliveries are made under stringent regulatory conditions. This is done with limited time and material available for detailed scientific investigations. This complex set of demands means scientists must find innovative methods to ask and answer the big questions. The references and resources below describe how scientists are approaching the this demanding challenge.

Reaction Insight Challenges

  • Reaction mechanism viability, conversion, and selectivity often remain unknown until late in the development cycle
  • Scientists are unable to sample with the frequency needed to understand reaction kinetics
  • Scientists rely on information obtained through visual observations which are sporadic, subjective, and rarely recorded
  • Expensive and over-burdened analytical resources that should focus on quality control are often deployed to troubleshoot or optimize challenging reactions
  • Many reaction steps require significant overhead to characterize (e.g. air sensitive, low temperature, and high pressure), meaning they are often not characterized at all
  • The critical process parameters that influence the performance of a reaction are often not recorded
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