Flow Chemistry | Benefits of Continuous Flow Chemistry

Flow Chemistry

Improve Safety, Reduce Cycle Time, Increase Quality and Yield

What is Flow Chemistry

What is Flow Chemistry
Flow Chemistry with PAT
Continuous Flow Reaction Of Highly Exothermic Reaction
Exothermic Reaction Flow Chemistry
Flow Chemistry Equipment
Accelerate Process Development with Flow Chemistry
Flow Chemistry Publications
MIcro Flow Cell for Flow Chemistry
Continuous Flow Chemistry Development

Applikationer

Applications for Continuous Flow Chemistry

kinetik af kemisk reaktion
Screening og optimering af katalyse, hydrogenering, polymersyntese og andre reaktive kemiske synteser

Kemisk reaktionskinetik
Undersøg kemiske reaktionshastigheder og mål kinetik inline

In situ-kemiske reaktionskinetikundersøgelser giver en forbedret forståelse af reaktionsmekanismen og vejen ved at tilvejebringe koncentrationsafhængighed af reagerende komponenter i realtid. Kontinuerlige data i løbet af en reaktion muliggør beregning af hastighedslove med færre eksperimenter på grund af den omfattende karakter af dataene.

Heat Transfer and Process Scale-up
How Heat Transport in Agitated Vessels Affects Process Scale-up

Scaling-up a chemical process from lab to manufacturing gives useful results only with accurate heat transfer coefficients. Measuring the jacket and reactor temperature (during the release of a well-defined amount of heat) allows researchers to accurately compute the thermal resistance which is used to model the heat transfer and make critical predictions for reactors at larger scale. Reaction calorimetry is essential to determine parameters that impact the heat transfer and the heat transfer coefficients to develop models to maximize the bandwidth of a manufacturing plant. 

Mass Transfer and Reaction Rate
Mixing in a Chemical Reactor and the Effect on Reaction Kinetics and Scale-up

Mixing is the reduction or elimination of inhomogeneity of phases that are either miscible or immiscible. Process scale-up and optimization require that the impact of mixing on the reaction rate be quantified. Automated, controlled experiments can be run in parallel in a laboratory reactor system to establish a mass transfer correlation, and provide a means to quickly adjust the gas/ liquid interface area and reactor volume. This achieves the desired conditions required for the scale-up or scale-down of a process.

Kemisk reaktionskinetik

In situ-kemiske reaktionskinetikundersøgelser giver en forbedret forståelse af reaktionsmekanismen og vejen ved at tilvejebringe koncentrationsafhængighed af reagerende komponenter i realtid. Kontinuerlige data i løbet af en reaktion muliggør beregning af hastighedslove med færre eksperimenter på grund af den omfattende karakter af dataene.

Heat Transfer and Process Scale-up

Scaling-up a chemical process from lab to manufacturing gives useful results only with accurate heat transfer coefficients. Measuring the jacket and reactor temperature (during the release of a well-defined amount of heat) allows researchers to accurately compute the thermal resistance which is used to model the heat transfer and make critical predictions for reactors at larger scale. Reaction calorimetry is essential to determine parameters that impact the heat transfer and the heat transfer coefficients to develop models to maximize the bandwidth of a manufacturing plant. 

Mass Transfer and Reaction Rate

Mixing is the reduction or elimination of inhomogeneity of phases that are either miscible or immiscible. Process scale-up and optimization require that the impact of mixing on the reaction rate be quantified. Automated, controlled experiments can be run in parallel in a laboratory reactor system to establish a mass transfer correlation, and provide a means to quickly adjust the gas/ liquid interface area and reactor volume. This achieves the desired conditions required for the scale-up or scale-down of a process.

Publikationer

Publications on Continuous Flow Chemistry

On-Demand Webinars

Continuous Flow Chemistry Using PAT
Eric Fang of Snapdragon discusses how continuous flow chemistry is applicable across the entire value chain. Early implementation of continuous flow...
Accelerated Process Development
Process development focused on continuous processes can utilize many of the same tools used in traditional batch processes. Nalas Engineering develops...
Development of Continuous Processes
David Ford of Nalas investigated an Oxidative Nitration reaction with a fast and highly exothermic oxidation step using reaction calorimetry and Proce...

White Papers

Hurtig analyse af kontinuerlige reaktionsoptimeringsforsøg
White paper - Hurtig analyse af kontinuerlige reaktionsoptimeringsforsøg - gennemgå, hvordan man optimerer kemiske reaktioner.
In Situ Monitoring of Chemical Reactions
'How to do more with less?' is a constant topic in chemical development laboratories as researchers need to quickly and cost-effectively deliver chemi...

Citations

ReactIR Citation List
Continuous measurements from infrared spectroscopy are widely used for obtaining reaction profiles, which are used to calculate reaction rates. This...

Relaterede produkter

Continuous Flow Chemistry Technology

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