
优化粒径分布
颗粒和液滴在化学品、消费品、造纸以及石油行业中无处不在。 颗粒生长、团聚、破碎、溶解以及改变形貌 - 所有这些均会对工艺性能与产品质量产生影响。 要获得成功,化学家和工程师必须充分了解与优化颗粒分布以控制工艺效率,例如稳定性、分离情况或流动特性等。 此外,必须很好地控制颗粒和乳化物分布,以确保可重复的产率、保质期与堆积密度。

颗粒与液滴处理
从早期开发到生产
- 加快新产品开发
- 尽早确定放大因素
- 快速确立工艺变量
- 建立确保高重现性批次的条件
- 树立提高工艺效率的信心
- 确立获得高质量产品的工艺品质
- 消除批次不合格
- 获得符合规定要求的产品(颗粒分布、产率和堆积密度)
- 缩短周期
- 优化分离速率
- 提高产品稳定性

在全工艺过程浓度条件下测量
运用在线颗粒尺寸与数目测量方法排除故障,并改进过程性能与产品质量。

实时颗粒与液滴分布测量
采用 ParticleView (FBRM) 和采用 ParticleView(PVM 技术)可实时测量颗粒与液滴分布,帮助做出更加明智、快速的决策。 通过 ParticleTrack 和 ParticleView 技术所掌握的颗粒相关信息能缩短数月的研发时间,使工艺生产效率实现最优,并对产品质量进行优化。 应用确保获得符合要求的粒径分布、稳定的工艺过程、最大程度地缩短后处理工艺的循环时间、避免在中试及生产中造成失败。
应用
PVM© technology can be used to detect the presence of unexpected polymorphs, even at concentrations below the detection limits of Raman or offline microscopy. By imaging thousands of particles per second, trace polymorph detection is possible where morphology changes exists.
絮凝是生化技术、石油、纸浆与造纸和采矿行业常用的一种分离法。 絮凝剂的长聚合物链可吸附到小颗粒上,引发颗粒架桥,促进大絮凝体的形成。 絮凝效率主要取决于混合时间和强度、有效絮凝剂的类型和浓度、加料速率、固体浓度和颗粒粒径。 高效絮凝可影响产品开发和规模扩大、下游分离性能、运行成本和产量。
The handling and processing of suspensions and emulsions is critical. Multiphase systems tend to be complex with many parameters, including overall process efficiency and economic profitability, being directly affected by the ability to consistently deal with the production, separation, and/or removal of solid particles and liquid droplets in suspension.
Liquid-liquid dispersions, or emulsions, are an excellent application for in situ droplet size measurement; sampling these systems for offline analysis can be unrepresentative as the sample can change by the time you measure it offine.
PVM© technology can be used to detect the presence of unexpected polymorphs, even at concentrations below the detection limits of Raman or offline microscopy. By imaging thousands of particles per second, trace polymorph detection is possible where morphology changes exists.
The handling and processing of suspensions and emulsions is critical. Multiphase systems tend to be complex with many parameters, including overall process efficiency and economic profitability, being directly affected by the ability to consistently deal with the production, separation, and/or removal of solid particles and liquid droplets in suspension.
Liquid-liquid dispersions, or emulsions, are an excellent application for in situ droplet size measurement; sampling these systems for offline analysis can be unrepresentative as the sample can change by the time you measure it offine.