Pipette Calibration Using a Balance

ISO 8655 Compliant Pipette Calibration and Routine Testing Services, Systems, and Equipment

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Pipette Calibration Using a Balance - ISO 8655

High-Throughput Experimentation (HTE)

Pipetting Guide ISO 8655

Pipette Calibration Workflow

Good Pipetting Practice
Pipette Routine Testing

Pipette Calibration Experts and Services

Pipette Calibration Services

Pipette Calibration and Routine Testing Devices

Rainin SmartCheck

Single Channel Pipette Testing

Pipette Testing with Analytical and Micro Balances

Multichannel Pipette Calibration Balances

Pipette Software and Accessories

Related Products

FAQ - Pipette Calibration

Frequently Asked Questions on Pipette Calibration & ISO 8655

What is pipette calibration?

Pipette calibration is a process that determines the expected volume with the actual volume delivered by a pipette together with the associated measurement uncertainty by an accredited institution. The purpose is to prove if the pipette is still within its manufacture or ISO8655 specifications to deliver accurate results. Pipettes out of tolerance can often be serviced, adjusted and re-calibrated.

Why is pipette calibration important?

Pipette calibration shows the difference between the expected and actual volume, which shall be within a given tolerance. If it is outside the tolerance, it could potentially lead to incorrect analytical results. Consequently, experimental results would not be reproducible and entire analyses might need to be redone. To detect an out-of-tolerance pipette early, it is recommended that users check pipette accuracy at regular intervals between calibrations.

Why is it important to test pipettes in-between service intervals?

Up to 35% of pipettes sent to a service provider for calibration are out-of-specification. If your pipette is one of these, you may need to investigate which previous analyses could have been affected by this error. How can you avoid this in the future? Performing regular pipette quick checks uncovers any malfunctions early and eliminates surprises at your next calibration service.

What’s a quick way to check pipette accuracy?

Pipette accuracy shall be checked regularly between calibrations to avoid out-of-tolerance results between calibrations. Our SmartCheck device is designed specifically for quick tests—simply pipette 4 dispenses into the SmartCheck at your selected process tolerance, and the SmartCheck will indicate pass/fail results with a simple green/red light.

What are two procedures for calibrating multichannel pipettes?

There are two acceptable methods for calibrating and testing multichannel pipettes:

  1. Each channel can be measured individually, one after another, with a single-channel pipette calibration balance. For this purpose, test liquid is aspirated by all channels together and collected from one channel at a time.
  2. A multichannel pipette calibration balance can be used to measure the test volume delivered from all channels in parallel by aspirating and emptying each channel simultaneously and analyzing each channel’s results individually.