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Hand Sanitizer Formulation and Concentration Determination

According to the Recommendations of the World Health Organization (WHO)

Hand hygiene is crucial to prevent infections by germs and microorganisms among people. To help countries and health-care facilities to adopt alcohol-based hand sanitizers as the gold standard for hand hygiene, the World Health Organization (WHO) has identified formulations, which can be produced from two different active ingredients:

a) Using ethanol 80% v/v

b) Using isopropyl alcohol 75% v/v

To learn more about the hand sanitizer formulation recommended by WHO, and how determine the concentrations using a density meter download the free PDF.

 

In addition, glycerol and hydrogen peroxide are further components of the formulations.

For an accurate concentration determination of hand sanitizers and each of its raw components, density measurement is the perfect analytical method. It allows for a quick and precise analysis in each step of the production process of hand rubs, such as:

  • Incoming raw materials: Purity check
  • Mixing / in-process: Control of dilution
  • Final product: Final concentration determination
  • Filling: Determination of filling volume

In this application note, we show how to control the concentration of hand sanitizers (final product) to ensure they follow the concentrations recommended by the WHO.

 

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Hand sanitizer formulation and concentration determination
Hand sanitizer formulation and concentration determination