Hydroquinone in Cosmetics
Determination using UV/VIS Spectroscopy at 289 nm
The application gives the method for determination of the content of hydroquinone in cosmetic products using UV/VIS spectroscopy at 289 nm using a METTLER TOLEDO UV/VIS Excellence Spectrophotometer.
Why is Hydroquinone content checked in Cosmetics?
Hydroquinone is an organic compound of the phenol family used as a skin-bleaching agent to lighten the area of darkened skin. Therefore, it is widely used in cosmetics. In 1982, FDA proposed the presence of 1.5 – 2.0% of hydroquinone in drugs as a GRASE (Generally Recognize as a Safe and Effective). Later in 2006, this rule has been withdrawn because evidences indicate hydroquinone as carcinogen and possible cause of ochronosis (skin darkening and disfiguration)
This application note includes:
- Introduction
- Sample Preparation and Procedures
- Solutions and Chemicals
- Instruments and Accessories
- Method in Detail
- Results and Remarks
And method files (.lmt and .xml) for direct import and implementation on the instrument.
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