Turbidity measurement: Success story in crystallization process
 
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Case Study

Turbidity measurement: Success story in crystallization process

Case Study

Achieving Accurate, Reliable, In-line Measurements During Crystallization

Turbidity in ChemPharma Crystallization
Turbidity in ChemPharma Crystallization

Accurate, Reliable, In-line Measurement

Turbidity measurement in pharma crystallization processes plays an important role. Determining the exact moment of saturation is central to achieving consistent product quality, and better crystal manufacturing operation and monitoring.
 


During API production, the most critical stage of the process is determining when saturation has been reached. If the temperature rise is halted too soon, API crystal formation will be poor. If the temperature rise is stopped too late, causing crystals to form at all can be problematic. An in-line turbidity monitoring system including an InPro 8200 sensor can indicate the exact moment saturation is complete.

This success story addresses the importance of turbidity measurements during crystallization. In-line measurement leads to improved process control thanks to reliable and reproducible detection of turbidity via fiber optic technology. It also reduces investment costs and enhances process safety.

Download the success story, "Accurate, Reliable, In-line Measurements – Turbidity System Increases Production Efficiency" to learn more about how a Chinese producer of antibiotics switched to in-line turbidity systems and improved crystallization efficiency and reduced costs.

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