Automatic Weighing – Systems for Laboratory

Next Level Powder and Liquid Dosing, Dilution Preparation, and Capsule Filling


Ready to boost accuracy and automate your lab processes?

3 in 1 – Automatic Laboratory Scale

Dispense in Milligrams

Dispense in Milligrams

Get repeatable dispensing results with guaranteed accuracy down to less than 1 mg. Use for both manual and automatic weighing to optimize your weighing processes.

Prepare Solutions and Dilutions

Prepare Solutions and Dilutions

Eliminate user error, increase accuracy, and save time.

Fill Capsules, Vials, and Bottles

Fill Capsules, Vials, and Bottles

Improve ergonomics and limit exposure to hazardous substances.

 USP 41 and 1251 Chapters on Balances

USP 41 and 1251 Chapters on Balances

Ensure Compliance with the Latest Revision 2025 / 2026

Learn more

Options for XPR Automatic Balance Configurations

Powder and Liquid Dispensing

Powder and Liquid Dispensing

The Q3 dosing module is an upgrade for an XPR Analytical Balance enabling both powder and liquid dispensing. Depending on the target min-weight or maximum capacity, the appropriate balance can be chosen. 

Liquid Dispensing Only

Liquid Dispensing Only

The QLX3 dosing module can dose liquids only. It is suited for dilutions or processes in which powders are dispensed manually and an exact solution is obtained with automatic liquid dispensing. 

Sample Changer

Sample Changer

The sample changer is an upgrade for the XPR Automatic Balance that allows for the automatic dispensing of up to 30 samples of powders and liquids in a single run.

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Frequently Asked Questions

For which applications can I use automatic weighing?

Multiple applications in various industries can benefit from automatic weighing, such as bottling for sales, sample preparation, capsule filling, or screening. Automatic scales are widely used in industries, such as fine chemicals, pharmaceuticals, CROs, CDMOs, or testing labs.

What is an automatic weighing balance?

The automatic balance can automatically dispense powders and liquids with high accuracy, in addition to performing solution preparation and serial dilutions. It improves workflows of sample preparation in the lab for qualitative and quantitative analysis of various analytical techniques including HPLC, GC, ICP, and NMR.

How can I improve the efficiency of sample preparation?

An automatic balance greatly reduces time spent on sample preparation. To further increase efficiency, an automatic balance can be upgraded with a sample changer, which can prepare samples while the operator focuses on other tasks in the lab.

What is gravimetric sample preparation?

Gravimetric sample preparation is weighing a sample, either manually or using automation, and then delivering the required amount of solvent to achieve a desired concentration. The solvent amount is calculated based on the actual amount of sample weighed and measured by its weight rather than volumetrically.

What is the lowest amount I can weigh automatically?

METTLER TOLEDO automatic balances (XPR226DRQ and XPR106DUHQ) show reliable performance for target weights above 0.30 mg. At this weight, 93% of measurements did not deviate more than 20% from the target weight.

How much time and sample can I save using automatic weighing?

The exact savings can be counted using a return-on-investment calculator. It can vary depending on the task time when working manually and sample costs. Generally, approximately 75% can be saved on sample and time when preparing the samples automatically.

How can I safely weigh potentially hazardous samples?

An automatic scale is the perfect solution for weighing hazardous samples. The system can work with limited technician interaction and can be easily placed in a safety enclosure or glove box.

What are the tricks to improve capsule filling?

An automatic balance with a sample changer is a useful solution for filling small batches (up to a few hundred) of capsules. Every capsule can be filled with a different amount of samples if necessary. This automated solution includes a specially designed powder dosing head in order to avoid spillage, error, waste, and save time.

What is a typical safety factor recommended by USP for manual and automated weighing?

According to USP <1251>, for stable laboratory conditions and trained operators, a safety factor of 2 is recommended.
For automated weighing (gravimetric dosing), a safety factor as low as 1.5 is recommended.

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