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White Paper on the Benefits of Digital Sensor Technology in the Pharma Industry

Manufacturing APIs in Harsh Chemical Processes

White Paper on the Benefits of Digital Sensor Technology in the Pharma Industry

White paper on recent developments in process analytical technology for reducing costs in the pharmaceutical industry.

The Easy Way to Reduce Costs in Drug Manufacturing

Reduce Manufacturing Costs Without Compromising Product Quality

Success story on condition based maintenance

Condition-Based Maintenance

At the Mitsubishi Chemical Corporation

How do ISM sensors contribute to process consistency?

To achieve process consistency, you need accurate and reliable sensors. Measurements from ISM sensors are very accurate because they use a measurement technology which better endures challenging processes. Measurements are calculated directly in the sensor and transmitted digitally, eliminating any losses caused by interference or long cables. Further, diagnostics in the sensor inform operators of a sensor’s need for maintenance. If a sensor requires maintenance, it can be exchanged for another that does not. Therefore, sensor reliability can remain very high.

Is interference a problem for analytical sensors?

Typically, analytical sensors output a weak, analog signal. Interference of the signal caused by nearby electromagnetic fields (e.g., from motors) and humidity in the environment can alter the signal or cause it to fluctuate. Also, transmitting the signal over long cables can lead to it being degraded and unreliable. Analytical sensors that output a digital signal are not affected by electromagnetic fields, moisture, or cable length.

What are challenging environments for analytical sensors?

Extremes of pressure, temperature, pH as well as conditions such a high percentage of solids in the medium can impact analytical sensors, leading to the need for frequent maintenance to restore measurement accuracy and also reduced sensor life. 

How do you know if a pH sensor’s working reliably?

For analog pH sensors it can be problematic to tell if a sensor is working correctly. However, there are various indications that a pH sensor is not operating as it should, e.g., slow response time, high membrane resistance, small slope, and large offset. ISM pH sensors continuously monitor their condition and predict how many days remain until maintenance, to restore correct operation, will be due. If maintenance is not required, you can be confident that an ISM sensor is working reliably.