Reakcijski kalorimetri za sigurnost procesa; razvoj i scale-up

Reaction calorimetry measures the heat released from a chemical reaction or physical process under process-like conditions and provides the fundamentals of the thermochemistry and kinetics of a reaction.

Calorimetric information is crucial when determining how chemical reactions can be transferred safely from lab to plant. Along with the chemical development workflow, reaction calorimetry provides the information needed for each of the individual steps and is subsequently converted into information to evaluate the risk, scalability and criticality of a process. Reaction calorimetry helps to identify issues related to heat and mass transfer or mixing, and allows the determination of the correct temperature, stirring or dosing profile online. Reaction calorimetry also uncovers unexpected behavior and makes other scalability issues visible and quantifiable.

Depending on the development stage, different types or quality of information is required. A wide range of reaction calorimetry workstations at different volumes, temperature ranges, accessories and capabilities are available.