Regular preventive maintenance can significantly reduce pipette failure rates. The most common pipette failures are:
- Seals/o-rings can leak after being exposed to damaging piston surfaces or sample contamination.
- Shaft ends wear over time, especially when high force is applied to mounting tips.
- Piston surfaces can deteriorate over time, leading to premature seal failure and pipette inaccuracy.
Because pipette failure rates vary from brand and type of pipette, a "risk-based" approach to pipette maintenance is recommended.