Particle Size Distribution & Shape Analysis

Particle Size Distribution Analysis

Real Time Particle Size & Shape Analysis For Laboratory and Process Environments

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Particle Size Distribution Analysis Inline

Particle size distribution is difficult to optimize, scale-up and analyze. With ParticleTrack with FBRM technology and ParticleView with P...

Particle size distribution is difficult to optimize, scale-up and analyze. With ParticleTrack with FBRM technology and ParticleView with PVM technology, METTLER TOLEDO is the world leader for real-time in situ particle system characterization and analysis. The ability to measure particles as they naturally exist in a process has dramatically improved the ability to understand, optimize and control particle and droplet systems.

Common applications include:

Since acquiring Lasentec in 2001, METTLER TOLEDO has continued to advance the development of FBRM and PVM. With thousands of installations worldwide from the R&D laboratory to the manufacturing plant, our probe-based technologies are acknowledged as the gold standard for particle size distribution analysis. Our technology measures and visualizes the rate and degrees of change in particle and droplet systems as they naturally exist in process.

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Real Time Particle Size & Count Analysis	Real-Time Microscopy for Crystals, Particles and Droplets
Probe-based instrument inserted directly into a process to study how particle size and count change over time with Focused Beam Reflectance Measurement (FBRM) technology.	Probe-based instrument inserted directly into a process to visualize particles using real-time microscopy with PVM technology.
Measure Particle Size and Count By monitoring particle size and count in real time, scientists can understand, optimize and scale-up processes confidently using evidence-based methods. Understand Without Sampling By tracking changes to size and count, as particles naturally exist in process, scientists obtain process understanding safely and with no time delay - even at extreme temperatures and pressure. Develop Processes Confidently By tracking particle size and count continuously as experimental conditions are varied, it is possible to optimize processes and obtain fit for purpose particles on a consistent basis. Deploy in the Lab and the Plant By monitoring manufacturing processes, upsets can be identified quickly and improvements can be made using evidence collected at full production scale.	Study Particle Size, Shape and Structure By obtaining real time microscope images of particles as they exist in-process, scientists obtain immediate and comprehensive process understanding for every particle system. Capture Elusive Mechanisms By visualizing crystals, droplets and other delicate particle structures, scientists can characterize transient events and elusive mechanisms that are critical for process and product quality. Investigate Critical Process Events An image-based trend, sensitive to changes in particle size and concentration helps scientists identify and then investigate important events reducing the time it takes to develop processes Obtain Evidence for Optimization By visualizing particles and particle mechanisms inline, scientists acquire unique understanding that supports smarter process development at a lower total.

Real Time Particle Size & Count Analysis

Probe-based instrument inserted directly into a process to study how particle size and count change over time with Focused Beam Reflectance Measurement (FBRM) technology.

Measure Particle Size and Count

By monitoring particle size and count in real time, scientists can understand, optimize and scale-up processes confidently using evidence-based methods.

Understand Without Sampling

By tracking changes to size and count, as particles naturally exist in process, scientists obtain process understanding safely and with no time delay - even at extreme temperatures and pressure.

Develop Processes Confidently

By tracking particle size and count continuously as experimental conditions are varied, it is possible to optimize processes and obtain fit for purpose particles on a consistent basis.

Deploy in the Lab and the Plant

By monitoring manufacturing processes, upsets can be identified quickly and improvements can be made using evidence collected at full production scale.

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Real-Time Microscopy for Crystals, Particles and Droplets

Probe-based instrument inserted directly into a process to visualize particles using real-time microscopy with PVM technology.

Study Particle Size, Shape and Structure

By obtaining real time microscope images of particles as they exist in-process, scientists obtain immediate and comprehensive process understanding for every particle system.

Capture Elusive Mechanisms

By visualizing crystals, droplets and other delicate particle structures, scientists can characterize transient events and elusive mechanisms that are critical for process and product quality.

Investigate Critical Process Events

An image-based trend, sensitive to changes in particle size and concentration helps scientists identify and then investigate important events reducing the time it takes to develop processes

Obtain Evidence for Optimization

By visualizing particles and particle mechanisms inline, scientists acquire unique understanding that supports smarter process development at a lower total.

See details

See less

Services

Service for Real Time Particle Size Analysis

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Explore our Services - Tailored to Fit your Equipment

We support and service your measurement equipment through its entire life-cycle, from installation to preventive maintenance and calibration to equipment repair.

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Publications

Publications on Particle Size Distribution

White Papers

Strategies To Control Crystal Size Distribution

This white paper discusses strategies to optimize crystal size distribution during process development and manufacturing.

Inline Particle Size Characterization

This white paper outlines how scientists and engineers can improve process understanding, product quality and process performance by applying inline p...

Particle Size Analysis for Process Optimization

This white paper introduces some of the most common particle size analysis approaches and how they can be deployed for the effective delivery of high...

Crystallization Process Design

Three world-class crystallization researchers present how to deliver significant improvements in crystallization process design.

Seeding a Crystallization Process

Seeding is a key step in optimizing a crystallization process, ensuring a consistent filtration rate, yield, polymorphic form and particle size distri...

Support

Support Documentation for ParticleTrack and ParticleView

G400 Hardware Support

Particle Track G400 Hardware Manual (pdf)

Positioning a ParticleTrack or ParticleView Probe (pdf)

ParticleTrack probes use Focused Beam Reflectance Measurement (FBRM) technology to track the rate and degree of change to particles and particle struc...

Changing ParticleTrack G400 Interchangeable Probe Tips (pdf)

This Quick Reference shows you how to quickly replace a ParticleTrack with FBRM G400 interchangeable probe tip and set the software to recognize the n...

Using the Purge Controller for ParticleTrack G400 or ParticleView V19 (pdf)

The Purge Controller is an optional accessory that can be purchased for use with ParticleTrack G400 and ParticleView V19. Purging is required where...

ParticleTrack G600 Hardware Manual (pdf)

This manual covers safety and quality information relating to the METTLER TOLEDO ParticleTrack G600 with FBRM (Focused Beam Reflectance Measurement) t...

ParticleTrack & ParticleView Onsite Training

Training and familiarization with ParticleTrack and ParticleView will ensure that all users can walk up to instruments and immediately bring value to...

V19 Hardware Support

Positioning a ParticleTrack or ParticleView Probe (pdf)

ParticleTrack probes use Focused Beam Reflectance Measurement (FBRM) technology to track the rate and degree of change to particles and particle struc...

Using the Purge Controller for ParticleTrack G400 or ParticleView V19 (pdf)

The Purge Controller is an optional accessory that can be purchased for use with ParticleTrack G400 and ParticleView V19. Purging is required where...

ParticleView V19 Hardware Manual (pdf)

This manual covers specific safety and quality information relating to the ParticleView V19 with PVM (Particle Vision Measurement) technology. The P...

ParticleView V19 Safety Manual (pdf)

This safety manual supplements the ParticleView V19 with PVM Technology Hardware Manual.

ParticleTrack & ParticleView Onsite Training

Training and familiarization with ParticleTrack and ParticleView will ensure that all users can walk up to instruments and immediately bring value to...

G600 Hardware Support

Positioning a ParticleTrack or ParticleView Probe (pdf)

ParticleTrack probes use Focused Beam Reflectance Measurement (FBRM) technology to track the rate and degree of change to particles and particle struc...

ParticleTrack G600 Hardware Manual (pdf)

This manual covers safety and quality information relating to the METTLER TOLEDO ParticleTrack G600 with FBRM (Focused Beam Reflectance Measurement) t...

ParticleTrack G600Ex Hardware Manual (pdf)

This manual covers safety and quality information relating to the ParticleTrack G600Ex with FBRM (Focused Beam Reflectance Measurement) technology.

ParticleTrack & ParticleView Onsite Training

Training and familiarization with ParticleTrack and ParticleView will ensure that all users can walk up to instruments and immediately bring value to...

Software Support

iC PVM Software Quick Start Guide (pdf)

This guide introduces a new user to the iC PVM software graphical user interface (GUI) and describes several choices for getting started. Create and r...

iC PVM Software Release Notes (pdf - 448 KB)

iC PVM Software User Install Guide (pdf)

iC PVM installation is wizard-guided. This guide includes detailed installation steps along with implementation information for the iC PVM administra...

iC FBRM Software Release Notes (pdf)

iC FBRM Data Review and Analysis Quick Reference (pdf)

iC FBRM Experiment Setup and Data Acquisition - Quick Reference (pdf)

iC FBRM Software User Guide (pdf)

iC FBRM Install Guide for Admins (pdf)

ParticleTrack & ParticleView Onsite Training

Training and familiarization with ParticleTrack and ParticleView will ensure that all users can walk up to instruments and immediately bring value to...

iC FBRM Software

iC FBRM delivers key information to help users develop a strong understanding of their particle system dynamics, optimize experimental design, speed d...