Solid Oral Dosage Formulation
Quantifying Dissolution & Disintegration
Quantifying tablet disintegration profiles in situ and in real time enables scientists to reliably understand the breakage and dispersion mechanisms that govern Active Pharmaceutical Ingredient (API) release rates. This essential process knowledge can support the prediction of in vivo drug release profiles during formulation development, and can help identify the root cause of inconsistencies during release testing.
The resulting mechanistic information complements traditional offline dissolution testing methods, and can support the development and release of bioavailable, stable, and manufacturable dosage forms.