Improving Synthesis through Flow Chemistry and Automation

Flow chemistry, continuous processing, or continuous flow chemistry, begins with two or more streams of different reactants pumped at specific flow rates into a single chamber, tube, or microreactor.  A reaction takes place, and the stream containing the resultant compound is collected at the outlet.  The solution may also be directed to subsequent flow reactor loops to generate the final product. Only small amounts of material are needed, which dramatically enhances process safety. Because of the inherent design of continuous flow technology, reaction conditions that cannot be safely achieved with batch reactions are possible. The result is product with higher quality, less impurity, and faster reaction cycle time.

Below are resources which demonstrate how technology is used in industry for increased safety, improved product quality, cost efficiency, and overall production flexibility.