This application note presents the determination of riboflavin content in polyethylene glycol (PEG) using a METTLER TOLEDO UV Vis spectrophotometer.
What Is Riboflavin?
Riboflavin or vitamin B2 is a water-soluble vitamin required for the normal function of aerobic cells. Milk and dairy products are rich sources of riboflavin. It has a beneficial effect on migraine headaches and its deficiency can cause skin disorders and hyperemia.
How to Determine Riboflavin Content Spectrophotometrically?
Riboflavin is frequently used as a colorant in pharmaceutical tablets. In effervescent tablets, PEG is used as an anti-foaming agent along with riboflavin. This application note describes the detailed calibration of riboflavin in PEG using a METTLER TOLEDO UV7 spectrophotometer at 268 nm. Riboflavin content in effervescent tablets is determined precisely using the calibration curve.





