HPIP with Rainin PureSpeed Tips - METTLER TOLEDO
White Paper

HPIP with Rainin PureSpeed Tips

White Paper

Fast, highly concentrated protein: High Performance IP with PureSpeed

Immunoprecipitation (IP) is a commonly used molecular biology technique where an antibody and antibody-binding resin are used to capture a specific antigen protein towards which the antibody has affinity. The High Performance Immunoprecipitation system, developed by Rainin, is a new technology for IP that simplifies binding, washing, and elution of the antibody and antigen protein.

The system relies on two components:

  1. PureSpeed Protein tips, that contain a small volume of protein A or protein G resin constrained at their distal end by nylon frits, 
  2. A programmable E4 XLS electronic pipette, and carries out repetitive, semi-automated up-and-down pipetting to aspirate and dispense antibody, antigen, and buffer solutions over the constrained resin.


Thank you for visiting www.mt.com. We have tried to optimize your experience while on the site, but we noticed that you are using an older version of a web browser. We would like to let you know that some features on the site may not be available or may not work as nicely as they would on a newer browser version. If you would like to take full advantage of the site, please update your web browser to help improve your experience while browsing www.mt.com.