Quantification, O/W Creams with Different Water Content

Sample

Creams with the following compositions (in %)

Application

Basic materials for the manufacture of creams

Conditions

Measuring cell: TGA850

Pan: Aluminum 100 µl, the lid was pierced, diameter of hole 1 mm

Sample preparation: As received, no preparation

TGA measurement: Heating from 20 °C to 200 °C at 2 K/min, blank curve corrected

Atmosphere: Nitrogen, 80 cm³/min

Interpretation

All the creams, with the exception of sample C, show a significant weight loss in the range 30 °C to 140 °C. This is caused by the evaporation of volatile components, above all water.

Evaluation

The individual steps are evaluated using the TGA curves

Conclusion

The results lie slightly higher than the values expected from the specified water content. This can be explained by assuming that other volatile components evaporate and in this way cause a weight loss that is greater than expected.

_{Quantification, O/W Creams with Different Water Content | Thermal Analysis Application No. HB839 | Application published in METTLER TOLEDO TA Application Handbook Pharmaceuticals}