PAT for Oligonucleotide and Peptide Synthesis - METTLER TOLEDO

PAT for Oligonucleotide and Peptide Synthesis


Ensure Your Yield, Purity and Cost Objectives Are Met

PAT for Oligonucleotide and Peptide Synthesis | March 30, 2022
PAT for Oligonucleotide and Peptide Synthesis | March 30, 2022

Learn how industry experts leverage data-rich experimentation, enabled by Process Analytical Technology (PAT), to ensure yield, purity and cost objectives are met for oligonucleotide and peptide synthesis. Practical experiences with PAT implementation for synthesis as well as process improvements that can be made by identifying, understanding and optimizing critical process parameters in real time will be discussed.

Past presentations included:

  • Commercialization of a Combined, Inline ATR-FTIR / Conductivity PAT System For Oligonucleotide Sequence Identification and Fault Detection
    Dan Hill - Biogen

  • Step Changes to Current Oligonucleotide Manufacturing - What PAT Will Be Needed in the Future
    Karsten Keller - Nitto Denko Avecia
2 hour(s)
Wed Mar 30 2022 15:00 +0000 [ English ]

Key topics:

  • Applying PAT process controls to oligonucleotide and peptide synthesis
  • PAT controlled process additions and identification of phosphoramidites
  • Formulation characterization of oligonucleotides
  • How PAT can enhance controls to improve yield and purity while lowering overall process costs

Who should attend?

  • Analytical chemists or engineers who support oligonucleotide and peptide synthesis
  • Process development scientists
  • CMC engineers
  • Chemical engineers
  • Downstream development scientists
  • Polymer chemists/scientists
  • Director of Process Analytical Technology
  • VP/Director of analytical development
  • VP/Director of oligonucleotide/peptide chemistry
  • VP/Director of process development
  • VP/Director of manufacturing
  • VP/Director of production engineering
  • VP/Director of technology innovation
  • Chief scientific officers

There is no cost to attend but registration is required, and space is limited.

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