Oiling Out in Crystallization | Liquid-Liquid Phase Separation

Oiling Out in Crystallization

Detect And Avoid Oiling Out (Liquid-Liquid Phase Separation)

What is Oiling Out in Crystallization?
Challenges with Oiling Out in Crystallization
Detect Oiling Out in Crystallization
Avoid Oiling Out in Crystallization
Miscibility Gaps
crystallization equipment
Introducing EasyViewer
Oiling Out Case Study from Eli Lilly
Oling Out Case Study from Bristol-Myers Squibb

Publications

White Papers

How to Optimize a Crystallization Step Using Simple Image Analysis
By quickly identifying unnecessary hold times and determining how cooling rate influences crystal growth and nucleation, the cycle time for an interme...
Understand Crystallization with In Situ Microscopy
Dynamic mechanisms key to understanding crystallization processes can now be observed with in situ microscopy. A white paper explains how leading chem...
A Guide to Crystallization and Precipitation
The quality of a crystallization process greatly influences the quality of the final product. Our new white paper introduces you to the fundamentals o...
Strategies To Control Crystal Size Distribution
This white paper discusses strategies to optimize crystal size distribution during process development and manufacturing.
Improve Industrial Crystallization
Industrial crystallization is an important separation and purification step in the chemical industry. A white paper shows how inline particle technol...
Seeding a Crystallization Process
Seeding is a key step in optimizing a crystallization process, ensuring a consistent filtration rate, yield, polymorphic form and particle size distri...
Scale-up of Batch Crystallization From Lab to Plant
Real-time monitoring of crystallization is shown to provide benefits leading to improved methods for process development, optimization and scale-up. T...
Best Practices For Crystallization Development
This white paper demonstrates the methodology chemists use to optimize critical crystallization parameters such as: Temperature profile Addition rates...
Particle Size Analysis for Process Optimization
This white paper introduces some of the most common particle size analysis approaches and how they can be deployed for the effective delivery of high...

Webinars

Designing Continuous Crystallization Platforms
This webinar describes an investigation into the characterization, design and operation of continuous crystallization. Robust crystallization process...
Eliminating Micronization Using Fine Particle Crystallization
Crystal engineering is applied when the crystal size distribution is too large to meet downstream specifications. By designing the crystallization to...
Calibration Free Supersaturation Assessment
The quantitative use of in situ ATR-FTIR for real time supersaturation assessment has been extremely well defined within the literature. However, thes...
metastable zone width (MSZW) crystallization
The webinar focuses on a semi-quantitative method for the optimization and scale-up of hydrodynamically limited anti-solvent crystallization process....
Improving Crystallization and Precipitation
This webinar introduces case studies and highlights best practices used to overcome crystallization and precipitation challenges. The focus will be on...

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