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Guide

Guide: Automation in Karl Fischer Titration

Guide

Optimize Your Workflow for Success

The guide describes ways to automate the Karl Fischer titration process. Automation permits more efficient use of space and/or resources. It may be used either to accelerate individual processes or to reduce the need for operator intervention during a workflow, which can help to improve productivity

Download the guide to automate Karl Fischer volumetric and coulometric titration for high throughput and reliable results.

The guide covers related topics including:

  • Basic Karl Fischer Titration Knowledge
  • How Automation Helps with Productivity
  • What can be Automated in KF titration
  • Automation Options for Karl Fischer Titration
  • Options for Flexible Karl Fischer Oven Automation

Additionally, it reviews application examples that can be modified for other sample types.


What can I automate for Karl Fischer Titration?

Karl Fischer titrations can be automated to improve both productivity and results reliability, and it can improve both ergonomics and safety for the end users.  An InMotion™ Karl Fischer Oven Autosampler and/or an InMotion Autosampler with the Karl Fischer Kit option can be used for automating Karl Fischer titration. 

With the InMotion Karl Fischer Oven Autosampler, up to 120 volumetric or coulometric automated water-specific titrations can be performed in a single sample series, with highly precise measurements down to a few ppm.

For samples that do not require the water to be extracted using the oven technique, automation of volumetric KF titrations is realized using an InMotion Autosampler with a Karl Fischer Kit option. Combined with any of the InMotion 100 mL racks, the Karl Fischer Kit allows for direct titration of up to 55 solid and liquid samples in the titration beaker.