Flow Chemistry | Benefits of Continuous Flow Chemistry

Flow Chemistry

Improve Safety, Reduce Cycle Time, Increase Quality and Yield

What is Flow Chemistry

What is Flow Chemistry
Flow Chemistry with PAT
Continuous Flow Reaction Of Highly Exothermic Reaction
Exothermic Reaction Flow Chemistry
Flow Chemistry Equipment
Accelerate Process Development with Flow Chemistry
Flow Chemistry Publications
MIcro Flow Cell for Flow Chemistry
Continuous Flow Chemistry Development

Applikasjoner

Applications for Continuous Flow Chemistry

Organisk syntese
Filtrer og optimer katalyse, hydrogenisering, polymersyntetisering og andre reaktive kjemiske synteser

Kjemikere som jobber med syntetisk organisk kjemi oppdager og utvikler innovative kjemiske reaksjoner og prosesser.

Impurity Profiling of Chemical Reactions
Continuous Automated Reaction Sampling Improves Productivity and Understanding for Chemists

Knowledge of impurity kinetics and mechanism of formation is important in determining reaction end-point in chemical and process development studies. Accurate, reproducible, and representative reactions samples are necessary for these studies.

kjemisk reaksjonskinetikk
Study Chemical Reaction Rates and Measure Kinetics Inline

Crystallization and Precipitation
Optimize Crystal Size, Yield and Purity

Optimization and scale-up of crystallization and precipitation to produce a product that consistently meets purity, yield, form and particle size specifications can be one of the biggest challenges of process development.

Heat Transfer and Process Scale-up
How Heat Transport in Agitated Vessels Affects Process Scale-up

Scaling-up a chemical process from lab to manufacturing gives useful results only with accurate heat transfer coefficients. Measuring the jacket and reactor temperature (during the release of a well-defined amount of heat) allows researchers to accurately compute the thermal resistance which is used to model the heat transfer and make critical predictions for reactors at larger scale. Reaction calorimetry is essential to determine parameters that impact the heat transfer and the heat transfer coefficients to develop models to maximize the bandwidth of a manufacturing plant. 

Mass Transfer and Reaction Rate
Mixing in a Chemical Reactor and the Effect on Reaction Kinetics and Scale-up

Mixing is the reduction or elimination of inhomogeneity of phases that are either miscible or immiscible. Process scale-up and optimization require that the impact of mixing on the reaction rate be quantified. Automated, controlled experiments can be run in parallel in a laboratory reactor system to establish a mass transfer correlation, and provide a means to quickly adjust the gas/ liquid interface area and reactor volume. This achieves the desired conditions required for the scale-up or scale-down of a process.

Organisk syntese

Kjemikere som jobber med syntetisk organisk kjemi oppdager og utvikler innovative kjemiske reaksjoner og prosesser.

Impurity Profiling of Chemical Reactions

Knowledge of impurity kinetics and mechanism of formation is important in determining reaction end-point in chemical and process development studies. Accurate, reproducible, and representative reactions samples are necessary for these studies.

Crystallization and Precipitation

Optimization and scale-up of crystallization and precipitation to produce a product that consistently meets purity, yield, form and particle size specifications can be one of the biggest challenges of process development.

Heat Transfer and Process Scale-up

Scaling-up a chemical process from lab to manufacturing gives useful results only with accurate heat transfer coefficients. Measuring the jacket and reactor temperature (during the release of a well-defined amount of heat) allows researchers to accurately compute the thermal resistance which is used to model the heat transfer and make critical predictions for reactors at larger scale. Reaction calorimetry is essential to determine parameters that impact the heat transfer and the heat transfer coefficients to develop models to maximize the bandwidth of a manufacturing plant. 

Mass Transfer and Reaction Rate

Mixing is the reduction or elimination of inhomogeneity of phases that are either miscible or immiscible. Process scale-up and optimization require that the impact of mixing on the reaction rate be quantified. Automated, controlled experiments can be run in parallel in a laboratory reactor system to establish a mass transfer correlation, and provide a means to quickly adjust the gas/ liquid interface area and reactor volume. This achieves the desired conditions required for the scale-up or scale-down of a process.

Publikasjoner

Publications on Continuous Flow Chemistry

On-Demand Webinars

Continuous Flow Chemistry Using PAT
Eric Fang of Snapdragon discusses how continuous flow chemistry is applicable across the entire value chain. Early implementation of continuous flow...
Accelerated Process Development
Process development focused on continuous processes can utilize many of the same tools used in traditional batch processes. Nalas Engineering develops...
Development of Continuous Processes
David Ford of Nalas investigated an Oxidative Nitration reaction with a fast and highly exothermic oxidation step using reaction calorimetry and Proce...

White Papers

Rapid Analysis of Continuous Reaction Optimization Experiments
The white paper - Rapid Analysis of Continuous Reaction Optimization Experiments - discusses how to optimize chemical reactions.
In Situ Monitoring of Chemical Reactions
'How to do more with less?' is a constant topic in chemical development laboratories as researchers need to quickly and cost-effectively deliver chemi...

Citations

ReactIR Citation List
Continuous measurements from infrared spectroscopy are widely used for obtaining reaction profiles, which are used to calculate reaction rates. This...

Relaterte produkter

Continuous Flow Chemistry Technology

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