FBRM 기술을 갖춘 ParticleTrack G600는 견고한 프로브 기반 기기로 대형 용기 또는 파이프라인에 직접 삽입되어 전체 공정 농도에서 입자와 액적 크기 및 개수 변화를 실시간으로 추적합니다. 공정 파라미터가 달라짐에 따라 입자, 입자 구조 및 액적이 지속적으로 모니터링되어 엔지니어는 공정을 효과적으로 모니터링, 문제 해결 및 개선할 수 있습니다.
입자 크기 및 개수는 다음을 포함하는 다중 위상 공정 내 성능에 직접적인 영향을 미칩니다.
엔지니어는 전체 생산 스케일에서 실시간으로 입자 크기 및 개수를 모니터링함으로써 공정 일관성을 모니터링하고 전략을 식별하여 상당한 공정 개선을 이룰 수 있습니다.
오프라인 분석을 위해 샘플링되고 준비하는 과정에서 입자는 변할 수 있습니다. 입자가 공정에 자연스럽게 존재함에 따라 엔지니어들은 입자 크기 및 개수 변화를 추적함으로써 극한의 온도 및 압력에서도 시간 지연 없이 안전하게 전체 생산 스케일에서의 공정 이해도를 얻습니다.
작동 조건이 변함에 따라 입자를 지속적으로 모니터링함으로써 작동이 원활하지 않은 공정의 근본 원인을 파악할 수 있습니다. 작업자는 공정 이상을 빠르게 식별할 수 있고 엔지니어는 까다로운 공정을 재설계하고 개선을 하기 위해 전체 생산 스케일에서 확보된 증거를 활용할 수 있습니다.
다양한 온도 및 압력 전반에 걸쳐 표준 플랜지, 딥 파이프 및 볼 밸브를 사용하는 반응기 또는 파이프라인에 유연한 장착 시스템을 통해 프로브를 설치할 수 있습니다. ATEX 등급의 옵션 인클로저 퍼지 및 Class I, Div 1 표준은 기기가 위험 장소에 안전하게 설치될 수 있도록 보장합니다.
| 측정 범위 | 0.5 – 2000μm |
| Temperature Range (Base/Field Unit) | |
| Base Unit Description | |
| Base Unit Dimension (길x높x폭) | 284 mm x 524 mm x 828 mm |
| Certifications | CE Approved, Class 1 Laser, NRTL Certified, CB Scheme Certified |
| Power Requirements | |
| For Use In | Pilot Plant or Production |
| 소프트웨어 | iC FBRM (Standard) iC Process for FBRM (Optional) |
| Scanning System | Pneumatic |
| Scan Speeds | 2m/s |
| Chord Selection Method (CSM) | Primary (fines) AND Macro (coarse) |
| Probe Diameter | 25mm |
| Probe Wetted Length | P: 1000mm R: 400mm X: custom T: 400m |
| Probe Wetted Alloy | C22 (Optional) SS316 (Standard) |
| 창 | 사파이어 |
| Standard Window Seals | Kalrez® |
| Probe/Window Options | TM Window Electropolish |
| Pressure Rating (Probe) | up to 250barg (custom) 10barg (standard) |
| Temperature Rating (Probe) | -80 to 150°C (custom) -10 to 120°C (standard) |
| Conduit Length | 15m [49.2ft] (standard) |
| Air Requirements | Scanner Requirements: Min. pressure: 4barg [60psig] Flow: 28.3 NL/min [1.0SCFM] |
| ParticleTrack Model | ParticleTrack G600 Process Technology for Pilot/Production |
| CE Approved, Class 1 Laser, NRTL Certified, CB Scheme Certified |
ParticleTrack G600/G600Ex represents a significant improvement over previous METTLER TOLEDO Lasentec FBRM technologies (D600/D600Ex).
Stuck Particle Correction Improves Consistent and Reliable Measurement - ParticleTrack can distinguish between particles stuck on the probe window and those moving in the process. These stuck particles can be removed from the data ensuring a consistent and reliable measurement for more experiments.
Improved Measurement Accuracy and Resolution - ParticleTrack uses state-of-the art digital signal processing methods to measure particle size with increased accuracy and resolution. These changes mean the measurement matches particle measurements such as laser diffraction and imaging more closely.
Wider Dynamic Range To Detect Critical Process Events - ParticleTrack measures changes in particle count to accurately eliminate concentration-related artifacts from the data and ensure improved sensitivity to changes in the particle system at higher concentrations. This allows critical process events to be detected that may previously have gone unobserved.
Two Measurements Acquired Simultaneously To Eliminate Need for Prior System Information or Trial Experimentation - ParticleTrack now collects two datasets simultaneously that are optimized for different types of particle systems. This eliminates the need for any a prior system information or trial experimentation to determine the optimal measurement method.
Improved Instrument to Instrument Repeatability - ParticleTrack technology was developed to ensure different lab and production instruments now measure much more closely, allowing changes in scale of measurement to be decoupled from differences in the probe used to measure them.
Voice of User
Senaputra, A., Jones, F., Fawell, P. D. and Smith, P. G. (2014), Focused beam reflectance measurement for monitoring the extent and efficiency of flocculation in mineral systems. AIChE J., 60: 251–265. doi: 10.1002/aic.14256.
"The [ParticleTracK]G400 also captures bimodal character in unweighted chord distributions, producing distinct peaks for aggregates and fines after suboptimal flocculation; such peaks are rarely well resolved in older FBRM".
"…the chord length measurement principle applied with the G400 probe leads to an enhanced sensitivity to species at the lower end of the measurement range relative to previous generation FBRM…"
"The mean square-weighted chord lengths reported from older generation FBRM for flocculated minerals are typically under 400 mm, and yet the naked eye can see much larger aggregates being formed in thickener feedwells. The G400 probe consistently measures larger chord lengths, and this is seen as a significant advantage"
George Zhou, Aaron J Moment, James F. Cuff, Wes A. Schafer,Charles Orella, Eric Sirota, Xiaoyi Gong, and Christopher J. Welch, Process Development and Control with Recent New FBRM, PVM, and IR. Org. Process Res. Dev., Just Accepted Manuscript, Publication Date (Web): 10 Jun 2014.
"Process analytical technologies (PATs) have played an important role in process development and optimization throughout the pharmaceutical industry. Recent new PATs, including in-process video microscopy (PVM), a new generation of focused-beam reflectance measurement (FBRM), miniature process IR spectroscopy, and a flow IR sensor, have been evaluated, demonstrated, and utilized in the process development of many drug substances. First, PVM has filled a technical gap by providing the capability to study morphology for particle engineering by visualizing particles in real time without compromising the integrity of sample. Second, the new FBRM G series has closed gaps associated with the old S series with respect to probe fouling, bearing reliability, data analysis, and software integration. Third, a miniaturized process IR analyzer has brought forth the benefits of increased robustness, enhanced performance, improved usability, and ease of use, especially at scale-up".
