Sampling of Chemical Reactions at Pfizer - METTLER TOLEDO
Вебинар в записи

Sampling of Chemical Reactions at Pfizer

Вебинар в записи

Automated Chemical Reaction Sampling

Dr. David Place reviews recent studies at Pfizer focused on the accurate and precise sampling of chemical reactions that are typically difficult to sample, including thick slurries, tri-phasic reactions, and oxygen-sensitive reactions.
Dr. David Place - Pfizer
32 Minutes

Learnings gained from the use of automated sampling in Pfizer's synthetic chemistry and process development labs are discussed.  Seven case studies presented include the sampling of the following reactions:

  • Ullman
  • Imidazolide
  • C-H Activation
  • De-Boc
  • Amination
  • Pd-Catalysed Carbonylation
  • Cl-Nitrobenzene Reduction

The improved data gained from the representative reaction samples provided not only better process understanding, but also enabled multi-tasking by chemists for more productive time in the laboratory.

After receiving a PhD in Organic Photochemistry and Photochemical Sciences from Bowling Green State University in 1998, Dr. David Place joined Eastman Kodak as a Research Associate. In 2005, Dr. Place joined Wyeth as a Principle Research Scientist and transitioned to Pfizer where he is currently a Research Scientist. Dr. Place has experience in automated chemical synthesis to optimization and screening of materials and reactions and his specialties include kinetics, Design of Experiments (DoE), process chemistry and informatics. With his ability to identify technical needs and implement changes to improve productivity, Dr. Place has established strong collaborative relationships in multi-facted projects and is an asset in the technical community.

Thank you for visiting We have tried to optimize your experience while on the site, but we noticed that you are using an older version of a web browser. We would like to let you know that some features on the site may not be available or may not work as nicely as they would on a newer browser version. If you would like to take full advantage of the site, please update your web browser to help improve your experience while browsing