PAT For Process Development and Scale-up - METTLER TOLEDO

PAT For Process Development and Scale-up


Featuring presenters from Bristol-Myers Squibb, Olon and Merck, this free online event on May 26 is for process chemists and engineers interested in developing and implementing strategic approaches to ensure product quality via process reproducibility and stability – in a resource-sparing manner.

PAT For Process Development and Scale-up
PAT For Process Development and Scale-up

Each presenter will share practical examples and case studies on the use of process analytics to overcome challenges around route selection, reaction understanding and monitoring, heat transfer and process safety.


  • PAT Enabled Development of a Semi-Continuous Drug Substance Manufacturing Process
    Ronald Carrasquillo-Flores, Ph.D. - Bristol-Myers Squibb

  • Data Rich Experimentation Across Scale: Leveraging PAT and Reactor Automation for Robust Process Design
    Keith A. Mattern - Merck & Co., Inc.

  • Continuous Safety Improvements to Avoid Runaway Reactions
    Alessandro Agosti - Olon

Each talk will be followed by a Q&A session with the presenter.

Stanislav Kasakov – METTLER TOLEDO
2 hours
Wed May 26 2021 13:00 +0000 [ English ]

Who Should Attend?

Process chemists and chemical engineers who need to:

  • Understand reaction mechanisms such as critical reaction parameters, kinetics, reaction intermediates or limits of heat exchange
  • Investigate 'What if' scenarios like cooling failure, mixing failure, heat exchange fouling or dosing disruptions
  • Consider the impact of scaling up delayed or auto-catalyzed reactions, Heat or product accumulations or heat transfer

There is no cost to attend but registration is required and space is limited..

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