Simultaneous image analysis and DSC measurements - METTLER TOLEDO

显微接口DSC

DSC显微镜系统.用于DSC仪器的显微镜选件

通过目视观察进行DSC测量

DSC曲线经常显示出一些无法理解的效应。在这种情况下,观察样品中发生了什么是很有帮助的。

显微镜选件中包含的设备

DSC显微镜系统包含CCD摄像头,其中带有与DSC温度程序同步的图像捕获和处理软件。

升级可能性

可在一分钟内将DSC升级为DSC显微镜系统,其中包括反射光显微镜测量功能。

物料号: 51143087

拨打电话询价
规格 - 显微接口DSC
技术
差示扫描量热法(DSC)
型号
光学分析
配件
适用
选件

文件记录

产品样本

DSC 3 Product Brochure
差示扫描量热法 (DSC) 是使用很广泛的热分析技术。差示扫描量热法 (DSC) 测量样品由于物理和化学性质的变化而发生的焓变与温度或时间的函数关系。
DSC 3+ Product Brochure
差示扫描量热法 (DSC) 是使用广泛的热分析技术。它测量样品由于物理和化学性质的变化而发生的焓变与温度或时间的关系。
The Future of Thermal Analysis Brochure
梅特勒-托利多的超越系列热分析系统为各种科研和工业应用提供了量身定制的解决方案。该系列包括 DSC、TGA、TMA 和 DMA 等技术,其优异的性能和创新技术将有助您走向所在领域前沿,并确保您获得高水平的瑞士品质、准确性及效率。
STARe 超越系列软件 产品样本
热分析是一种在很多不同领域广泛使用的成熟分析方法。该方法为实验室提供了在质量保证和控制过程和产品开发以及研究方面具有价值的结果和全新信息。很多问题都可结合不同热分析技术加以解决。

单页样本

Datasheet: DSC-Microscopy System
The system provides images of samples at predefined temperature or time intervals. A further evaluation possibility is to quantify color differences b...

附件

Application Examples


   
DSC-microscopy analysis of an active pharmaceutical ingredient

The melting point is an important characteristic property of a substance. The DSC measurement of an active pharmaceutical substance (API) yielded a curve with two main peaks – an endothermic peak with a maximum at 210.8 °C and an exothermic peak at about 228 °C. A smaller peak was also apparent between these two peaks at about 214 °C. The initial interpretation was that the endothermic peak at 210.8 °C is due to melting. The DSC-microscopy results, however, told a different story. No melting was observed at 211 °C – the first signs were detected at about 214 °C. Clearly, the endothermic DSC peak is not caused by a melting process. The color change of the molten substance leads one to conclude that it decomposes immediately on melting. The small DSC peak observed at about 214 °C is therefore the sum of two simultaneously occurring effects – endothermic melting and exothermic decomposition. Separate TGA-MS measurements showed that the endothermic DSC peak at 210.8 °C is caused by the evaporation of water of crystallization.
 



Dehydration of CoCl2 hexahydrate

The images illustrate the dehydration process of cobalt (II) chloride hexahydrate when it is heated from 30 °C at 1.5 K/min. The initial ruby-red color becomes lighter and lighter until it suddenly changes at about 55 °C. Further color changes are observed between 100 °C and 120 °C and at 160 °C. The differences can be quantified by calculating a curve showing image brightness as a function of temperature. The DSC curve shows a broad endothermic peak up to 80 °C with a sharp peak at about 55 °C superimposed on it. Two further endothermic peaks follow at about 104 and 130 °C. The brightness first increases and then suddenly decreases at about 55 °C. Afterward, it increases again in several steps. The peak at about 55 °C is due to a change in crystalline structure. The images around 55 °C show small droplets of water on the surface of the crystals. This indicates that part of the water of crystallization eliminated from the crystal lattice during the solid- solid transition collects on the surface of the crystals and then evaporates. This is completed by about 80 °C. The two broad endothermic peaks on the DSC curve and the step-like changes in the brightness are due to further loss of water of crystallization.

耗材

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显微接口DSC