Characterization of the Melting Behavior, Vanillin

Sample

Vanillin

Application

Flavoring agent

Conditions

Measuring cells: DSC820 or TGA850

Pan: Aluminum 40 µl, with pierced lid or open

Sample preparation: As received, no preparation

DSC measurement: Heating from 30 °C to 250 °C at 10 K/min

TGA measurement: Heating from 30 °C to 250 °C at 10 K/min, blank curve corrected

Atmosphere: Nitrogen, DSC: 50 cm³/min, TGA: 20 cm³/min

Interpretation

The melting curve provides a survey of possible events that can occur during the measurement. This information can not be gained from simple melting point determinations with TOA. For instance the DSC curve shows a slight shift of the baseline after the melting process. The TGA curve shows no weight loss in this region, which indicates that the DSC baseline shift is caused by a change in the specific heat capacity (c_p). The SDTA signal of the TGA850 allows a qualitative evaluation of the melting behavior along with the TGA measurement.

An increasing weight loss occurs at temperatures above 150 °C because the vanillin evaporates and decomposes.

Evaluation

Onset temperature determination and integration of the melting peak of the DSC curve.

Conclusion

The DSC is suitable for the rapid determination of melting points and heats of fusion. Additional information can be gained from a TGA measurement.

_{Characterization of the Melting Behavior, Vanillin | Thermal Analysis Application No. HB800 | Application published in METTLER TOLEDO TA Application Handbook Pharmaceuticals}