Daiichi Sankyo have developed an automated sampling and quantitative HPLC analysis system by combining EasySampler with Shimadzu's HPLC and switching valve (FCV-20AH2).
Normally, the EasySampler collects reaction aliquots from solution, prepares diluted samples, and stores them in a vial carousel for subsequent off-line analyses. In this study, instead of using the EasySampler vial carousel, the tubing was connected to HPLC and investigated an automated on-line quantitative analysis in real time. After optimizing the conditions, we confirmed that the accuracy and reproducibility were sufficient for practical use.
Process Chemist, Daiichi Sankyo
Makoto Michida is a process chemist at Daiichi Sankyo for 25 years, with recent interest in lab automation and automating medium-scale synthesis experiments. His expertise and passion for automation have been recognized, and he is expected to contribute to future research in the field.