Thermal Analysis of Pharmaceuticals
Thermal analysis covers many important application areas in the pharmaceutical industry. Its techniques allow pertinent material properties such as heat capacity, mass or enthalpy to be easily and quickly measured with respect to temperature or time.
Our Thermal Analysis of Pharmaceuticals handbook describes the application possibilities of single, simultaneous and hyphenated thermal analysis techniques (DSC or TGA, TGA/DSC and TGA-EGA, respectively) with the aid of 47 carefully selected examples. Typical applications areas of thermal analysis, include:
Active pharmaceutical ingredients (API): Polymorphism, melting point, glass transition of amorphous fractions, content determination, effect of moisture, existence of solvates, purity analysis.
Formulations: Compatibility of excipients, shelf life, thermal degradation, moisture determination.
Packaging materials: Testing of primary and secondary packaging materials, thermal stability, moisture determination, coatings, blister package interactions, effect of repackaging.