Dissolved CO₂ in Upstream Bioprocessing - METTLER TOLEDO
Webinare live

Dissolved CO₂ in Upstream Bioprocessing

Webinare live

A live Online Event hosted by American Pharmaceutical Review

Moderator:  American Pharmaceutical Review

Duration: 1 Hour

10/24/2019 10AM EST / 1PM EST

Accumulation of CO2 in fermentation and cell cultures can become a significant problem affecting productivity and product quality of recombinant proteins and monoclonal antibodies (mAbs). During this webinar, the following topics will be approached with a technical perspective:

  • Measuring CO2 inline and monitor its accumulation
  • Elevated CO2 partial pressure (pCO2) can alter protein glycosylation and affects the purity of mAbs.
  • pCO2 is affecting media and intracellular osmolality
  • Measuring pCO2 offline versus inline
  • Monitoring and controlling CO2 during a fermentation

A list of scientific references for fermentation and cell culture processes will be also communicated and available after the webinar.

American Pharmaceutical Review
1 hour
Thu Oct 24 2019 16:00 +0200 [ English ]
Thu Oct 24 2019 19:00 +0200 [ English ]

Your Online Event Presenter :

Olivier Berteau – Global Industry Manager, Pharmaceutical, METTLER TOLEDO

Olivier Berteau graduated from Institut du Genie Chimique, Toulouse France with a BS in Chemical Engineering. He has more than 25 years of hands-on operating experience within the biopharmaceutical industry with extensive upstream bioprocess expertise, process development, and analytical solutions. A unique combination of engineering and bioprocessing skills based upon experience for fermentation and cell culture processes at preclinical and clinical development phase. His experience also includes USP/DSP bioprocessing, perfusion, single-use technologies and several breakthrough-bioprocessing technologies. Along with his many years of biotech experience and a passion for innovation, his areas of focus are: cell culture and fermentation processes, design of equipment and instrumentation, cGMP environments, continuous manufacturing and process understanding/deviation.

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