Certain attributes of turbulent mixing have been identified to impact key crystallization characteristics, including:
This presentation focuses on the use of Process Analytical Technology (PAT) and Computational Fluid Dynamics (CFD) in understanding common industrial crystallization challenges and in turn facilitate the production of methods for the scale-up and scale-down of this process. A "scale-up toolbox" is used to optimize bench scale crystallizations to produce efficient, repeatable crystallizations. Three case studies are included:
Mark Barrett received his Ph.D. in Chemical Engineering from University College Dublin (UCD). His thesis work focused on crystallization development and scale-up. Prior to co-founding APC in 2011, Mark worked for Solid State Pharmaceutical Cluster (SSPC) and Schering Plough.