In order to fully understand chemical reactions, chemists must address the following:
Traditionally, to answer these questions, samples must be taken for offline analysis, such as HPLC. However, for chemistries that are toxic, under pressure, or conducted in extreme temperatures, this procedure is not straightforward and chemists must wait for the results before reaction analysis can begin.
In situ Fourier Transform Infrared (FTIR) spectroscopy provides detailed information about reaction initiation, endpoint, and kinetics for real-time reaction understanding and optimization.
ReactIR FTIR spectroscopy is inserted into the reaction vessel where it collects spectra over time at reaction conditions. Because absorbance is proportional to concentration, you can profile spectra over time for reaction profiles that provide a clear map of reaction progression for representative and real-time reaction analysis.
Immediate Results:
ReactIR provides in situ reaction understanding without the wait for LC results.
Improve Understanding:
Allows real-time monitoring of a reaction and provides detailed information about reaction initiation, conversion, intermediates and endpoint.
Suitable for:
Eric Fang of Snapdragon discusses how continuous flow chemistry is applicable across the entire value chain. Early implementation of continuous flow chemistry in drug discovery and development unlocks the greatest value.
Charles Goss presents examples illustrating how GlaxoSmithKline (GSK) monitors flow and batch chemistry unit operations in both laboratory and pilot plant reactors.
In-situ FTIR spectrometers enable scientists to gain insight into their reactions and processes in a wide range of applications. Optimize reaction variables with inline FTIR instruments.