Integrated Flow Development at PharmaBlock

Transitioning from Batch to Continuous Flow: Scaled-Up Solutions for High-Risk Reactions

Program Overview

  • Evaluate the direct impact of batch-to-flow transformation on cost, sustainability, and key performance indicators
  • Discover practical technical solutions to mitigate thermal runaway, poor mass transfer, and strict material selection challenges across extreme temperature and pressure ranges.
  • Learn how to combine kinetic modeling, CFD simulation, inline Raman analytics, and Bayesian closed-loop intelligent optimization to automate and support industrial scale-up.

Moving from traditional batch production to continuous flow chemistry offers massive efficiency gains, but navigating scale-up bottlenecks can be daunting.

In this technical webinar, Aimin Jiang from the PharmaBlock Research Institute (PBRI) presents, Integrated Flow Development at PharmaBlock, breaking down their end-to-end integrated continuous flow development system. Built on robust cross-disciplinary collaboration, this system leverages engineering, computational modeling, and real-time analytical monitoring to successfully scale hazardous and complex chemistry.

Target audience

  • Process Chemists and Chemical Engineers

  • R&D Directors and Lab Managers

  • Pharma and Agrochemical Development Scientists

  • Automation and Analytical Technology Specialists

  • About the Presenter

    Aimin Jiang

    Aimin Jiang

    PharmaBlock

    Boasting 15 years of end-to-end experience in lab-scale R&D, process development and manufacturing of pharmaceutical building blocks, Aimin Jiang has profound expertise in continuous flow process development and scale-up production. He has successfully delivered over 200 kilogram-scale and higher pharmaceutical building block manufacturing projects during his tenure. As a core member of PharmaBlock’s professional process development team, he has long been involved in team building and daily operational management, gaining solid and comprehensive experience in overall project management.

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