Karl Fischer Titrators

During the automatic pre-titration on a METTLER TOLEDO Karl Fischer titrator, the instrument quickly doses reagent to consume any moisture that crept into the cell between runs. 

The built-in burette handles this pre-titration dosing without an operator, immediately after you tap a OneClick shortcut; every dispensed volume is written to the result file for full traceability. While the dosing runs, KF Solvent Control monitors solvent quality, and the StatusLight on the terminal or tower shifts to its ready indication once the cell is dry, giving you a clear, at-a-glance green light to load the first sample. 

Conditioning the cell first is critical because it removes blank water, stabilizes drift, and guarantees that the very first measurement already meets the ppm-level accuracy of Karl Fischer demands. By automating this step, and recording every action in LabX, Excellence T5, T7, and T9 titrators protect data integrity, cut hands-on time, and keep regulated workflows compliant from sample #1 onward.

METTLER TOLEDO instruments don’t rely on a fixed “every-X-hours” schedule, instead they watch the solvent itself. Excellence T-Series titrators equipped with the optional KF Solvent Manager (and its firmware feature, KF Solvent Control) keep a running tally of the total water titrated or the number of samples analyzed; when the user-defined limit is reached the titrator triggers a fully automatic drain-and-refill, recording the event in LabX for audit-ready traceability. EVA V1/V3 and Compact C1/C3 models ship with an automatic solvent-exchange pump as standard, though a pump-free configuration is available if preferred, and the pump can be called by a OneClick shortcut or embedded in a method to refresh solvent after heavy sample loads, eliminating manual siphoning. 

For high-throughput workflows,an autosampler can be set to trigger the Solvent Manager after a preset number of samples; the KF oven operates independently and does not interface with the solvent-exchange system.  

In short, replace (or let the instrument replace) the solvent when the built-in Solvent Control flags it as spent, a condition-based approach that protects data quality far better than any time-based rule of thumb.

Persistent high Karl Fischer drift after several samples often indicates the reagent or anolyte is exhausted, or that the sample is causing side-reactions; in either case the quickest cure is a fresh solvent exchange. On an Excellence T5, T7 or T9, or any Compact KF titrator, fitted with the optional KF Solvent Manager, simply tap the OneClick Solvent Control shortcut: the titrator checks the cumulative water or sample count and, once your preset limit is exceeded, performs a sealed drain-and-refill in one step. No cell opening, recalculation or manual siphoning is required, and the event is time-stamped in LabX while the StatusLight turns green as soon as the new solvent stabilizes.

EVA V1/V3 instruments and InMotion KF oven systems achieve the same fast recovery when equipped with the optional automatic solvent-exchange pump. A dedicated dPump, when installed on an EVA, can be triggered from the touchscreen or embedded in the method so drift never climbs between large sample batches, while an InMotion KF autosampler can be configured, via the titrator’s Solvent Manager, to trigger an exchange automatically after a user-defined number of runs, keeping overnight series on spec without operator intervention.

Yes — sealed-vial automation is built in.

Pair an InMotion KF Oven Autosampler with an EVA V3 (volumetric) or EVA C3 (coulometric) titrator; V1 and C1 do not drive the oven but can automate low-volume liquid samples via the 6-position InMotion KF Six   autosampler. The oven pierces each sealed vial, heats the solid or highly viscous sample to your Temperature   set-point, and sweeps only the released water vapor into the cell, no messy syringe injections, no matrix interferences.

Upgrade path as workloads grow starts with the compact KF Flex Oven (26 positions, 10 mL vials only and up to 120 samples per series); you can then move the same titrator to a KF Pro Oven rack, which offers the same 26-position footprint but accepts 5, 10 or 20 mL vials, supports Temperature Scan, and likewise handles up to 120 samples per series.

For parallel workflows, connect the oven to an Excellence T7, or to a dual-workflow T9, which can drive two independent InMotion KF ovens or other autosamplers simultaneously, doubling throughput while logging every action in LabX.

METTLER TOLEDO Karl Fischer instruments keep you away from methanol and iodine thanks to closed-loop solvent handling and smart hardware monitors.  On Titration Excellence instruments (T5, T7, T9)   the optional KF Solvent Manager performs every drain-and-refill through sealed tubing only after Solvent Control reaches the user-defined limit for total water titrated or samples processed . The built-in LevelSens waste sensor stops the sequence before any overflow can occur, eliminating manual siphoning and open-cell exposure. EVA titrators offer the same closed solvent lines and add a detachable 2.5 m touchscreen, so OneClick routines can be launched at a safe distance, further reducing contact with hazardous liquids or vapors.

For automated solid or highly viscous samples, an InMotion KF Oven pierces pre-crimped vials and sweeps only the released water vapor into the titration cell, keeping reagents sealed inside the oven and cell at all times. Every solvent change and sample run is logged in LabX for audit-ready traceability. Together, these closed-system designs, liquid-level sensors and remote-operation features create a Karl Fischer workflow that meets safety regulations and keeps operators clear of reagent exposure.

LabX acts as a secure, central SQL hub that captures every signal, result and user action from METTLER TOLEDO titrators and InMotion autosamplers, then locks those records behind role-based access, electronic signatures and a tamper-proof audit trail. All edits to methods are version-tracked automatically, while release workflows ensure only approved procedures run on the instrument.

Because the database, user-management and e-sig controls meet FDA 21 CFR Part 11, EU Annex 11 and GAMP 5 guidelines, laboratories can export validated PDF or CSV reports straight to LIMS/ELN systems without manual transcription. EVA V- and C-Series titrators, Excellence T5/T7/T9, and every InMotion KF Oven or sample changer connect via the same LabX licenses, giving both routine and high-throughput workflows identical, compliance-ready data protection.

The FFA control algorithm, built into the EVA V1/V3 volumetric titrators (and their coulometric C-series twins), keeps the iodine concentration in the cell high and stable, so the reaction with water proceeds at its fastest possible rate. A digital dSens M143 electrode measures the current 10 times per second; FFA extrapolates those readings in real time to forecast exactly how much reagent is still needed, then drives the 120 000-step dDrive burette to add it without overshoot. The result is a reaction that hits the end-point quickly while still meeting DIN/ISO accuracy limits.

Because every forecasted dose is smaller and better-timed, samples with 100 ppm to 100% water finish up to 30% sooner, yet reagent usage stays lean, an advantage when you’re pushing high daily throughput or running trace-level tests in batteries, electronics and petrochemicals. EVA’s touchscreen stores the algorithm parameters with each method and logs every dispensed µL to LabX, so laboratories gain both productivity and fully audit-ready traceability.